SCHEMBL23974604

SCHEMBL23974604

C#Cn1c(=O)n(C)c2c1c(=O)n(C)c(=O)n2C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2B P29275 5/20 0.38
PIK3CD O00329 1/20 0.35
POLB P06746 1/20 0.35
ADORA3 P0DMS8 1/20 0.35
CNR1 P21554 1/20 0.35
ACHE P22303 1/20 0.35
ADORA2A P29274 1/20 0.35
ADORA1 P30542 1/20 0.35
NTSR1 P30989 1/20 0.35
MC3R P41968 1/20 0.35
NOTUM Q6P988 1/20 0.35
SIRT3 Q9NTG7 1/20 0.35
GDA Q9Y2T3 1/20 0.35
NR2E1 Q9Y466 1/20 0.35
LGMN Q99538 1/20 0.35
KMT2A Q03164 2/20 0.33
LMNA P02545 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23974793 0.86 ADORA2B (0.37) ADORA2BPIK3CDPOLBADORA3CNR1
SCHEMBL23974606 0.84 ADORA2B (0.32) ADORA2B
SCHEMBL24404209 0.75 ADORA2B (0.31) ADORA2BPIK3CD
SCHEMBL2817943 0.75 ADORA2B (0.43) ADORA2BPIK3CDPOLBADORA3CNR1
SCHEMBL22899094 0.71
SCHEMBL23974586 0.68 ADORA2B (0.65) ADORA2BPIK3CDPOLBADORA3CNR1
SCHEMBL5414791 0.67 ADORA2B (0.48) ADORA2BPIK3CDPOLBADORA3CNR1
SCHEMBL15085518 0.67 ADORA2B (0.39) ADORA2BPIK3CDPOLBADORA3CNR1
SCHEMBL22899002 0.65
SCHEMBL9972939 0.65 KMT2A (0.42) ADORA2BPIK3CDPOLBADORA3CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210344045-A1 Nonaqueous Electrolyte Solution and Nonaqueous Secondary Battery ASAHI KASEI KABUSHIKI KAISHA (JP) 2021-11-04 US disclosed