Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 17/20 | 0.49 |
| ▸ | RIPK2 | O43353 | 12/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | BIRC3 | Q13489 | 3/20 | 0.45 |
| ▸ | BIRC2 | Q13490 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23975269 | 1.00 | XIAP (0.49) | XIAPRIPK2ESR1BIRC3BIRC2 | |
| SCHEMBL23975507 | 1.00 | XIAP (0.49) | XIAPRIPK2ESR1BIRC3BIRC2 | |
| SCHEMBL23975195 | 1.00 | XIAP (0.49) | XIAPRIPK2ESR1BIRC3BIRC2 | |
| SCHEMBL23975461 | 1.00 | XIAP (0.49) | XIAPRIPK2ESR1BIRC3BIRC2 | |
| Lcl-161 SCHEMBL3688581 | 0.98 | XIAP (0.50) | XIAPRIPK2ESR1BIRC3BIRC2 | |
| Lcl-161 SCHEMBL18663754 | 0.98 | XIAP (0.50) | XIAPRIPK2ESR1BIRC3BIRC2 | |
| Lcl-161 SCHEMBL1275371 | 0.98 | XIAP (0.50) | XIAPRIPK2ESR1BIRC3BIRC2 | |
| Lcl-161 SCHEMBL1275554 | 0.98 | XIAP (0.50) | XIAPRIPK2ESR1BIRC3BIRC2 | |
| Lcl-161 SCHEMBL21064744 | 0.98 | XIAP (0.50) | XIAPRIPK2ESR1BIRC3BIRC2 | |
| Lcl-161 SCHEMBL19164873 | 0.98 | XIAP (0.50) | XIAPRIPK2ESR1BIRC3BIRC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021220178-A1 | IAP ANTAGONISTS AND THEIR THERAPEUTIC APPLICATIONS | COMINNEX ZRT. (HU) | 2021-11-04 | — | — | WO | disclosed |