Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLNR | O43193 | 6/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL377588 | 0.87 | CHRM4 (0.45) | MLNRFAAHMEN1KMT2AACHE | |
| SCHEMBL377748 | 0.85 | MLNR (0.49) | MLNRFAAHKMT2AKCNH2 | |
| SCHEMBL377770 | 0.82 | CHRM4 (0.42) | MLNRFAAHACHEAGTR2 | |
| SCHEMBL3570120 | 0.82 | MLNR (0.53) | MLNRGAAMEN1KMT2A | |
| SCHEMBL3559461 | 0.81 | MLNR (0.60) | MLNRPRKAA2 | |
| SCHEMBL378303 | 0.81 | MLNR (0.55) | MLNRGAAHRH3OPRK1FAAH | |
| SCHEMBL2766677 | 0.79 | MLNR (0.48) | MLNRKMT2A | |
| SCHEMBL2397555 | 0.78 | MLNR (0.52) | MLNRGAAHRH3 | |
| SCHEMBL377489 | 0.78 | MLNR (0.41) | MLNRFAAH | |
| SCHEMBL377408 | 0.77 | MLNR (0.76) | MLNRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8012981-B2 | Benzylpiperazine derivatives as motilin receptor agonists | GLAXO GROUP LIMITED (GB) | 2011-09-06 | — | — | US | disclosed |