Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30225327 | 1.00 | IGF1R (0.32) | IGF1RKDM4E | |
| SCHEMBL23975736 | 1.00 | IGF1R (0.32) | IGF1RKDM4E | |
| SCHEMBL23986874 | 0.78 | TRPM8 (0.36) | IGF1RKDM4E | |
| SCHEMBL30118574 | 0.78 | TRPM8 (0.36) | IGF1RKDM4E | |
| SCHEMBL23975771 | 0.78 | TRPM8 (0.36) | IGF1RKDM4E | |
| SCHEMBL23986855 | 0.78 | TRPM8 (0.36) | IGF1RKDM4E | |
| SCHEMBL24702101 | 0.74 | IGF1R (0.31) | IGF1R | |
| SCHEMBL12526910 | 0.68 | EHMT2 (0.44) | — | |
| Hydrochloric Acid SCHEMBL1748535 | 0.67 | EHMT2 (0.44) | — | |
| SCHEMBL11290218 | 0.66 | HTT (0.45) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222483-A1 | METHODS OF USE FOR PYRIMIDINES AS FERROPORTIN INHIBITORS | GLOBAL BLOOD THERAPEUTICS, INC. (US) | 2021-11-04 | — | — | WO | disclosed |
| WO-2021222363-A1 | CYCLOALKYL PYRIMIDINES AS FERROPORTIN INHIBITORS | GLOBAL BLOOD THERAPEUTICS, INC. (US) | 2021-11-04 | — | — | WO | disclosed |