Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.73 |
| ▸ | MAOB | P27338 | 3/20 | 0.73 |
| ▸ | NPC1 | O15118 | 4/20 | 0.63 |
| ▸ | RAB9A | P51151 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.55 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL522503 | 0.85 | MAOA (1.00) | MAOAMAOBNPC1RAB9AMAPT | |
| SCHEMBL30373802 | 0.85 | MAOA (1.00) | MAOAMAOBNPC1RAB9AMAPT | |
| Hydrochloric Acid SCHEMBL4509967 | 0.83 | MAOA (0.96) | MAOAMAOBNPC1RAB9AMAPT | |
| Hydrochloric Acid SCHEMBL2085180 | 0.83 | MAOA (0.96) | MAOAMAOBNPC1RAB9AMAPT | |
| SCHEMBL12994650 | 0.83 | NPC1 (0.68) | MAOAMAOBNPC1RAB9AMAPT | |
| SCHEMBL12669965 | 0.83 | MAOA (0.69) | MAOAMAOBNPC1RAB9AMAPT | |
| SCHEMBL20837976 | 0.82 | MAOA (1.00) | MAOAMAOBNPC1RAB9AMAPT | |
| SCHEMBL10557233 | 0.82 | MAOA (0.73) | MAOAMAOBNPC1RAB9AMAPT | |
| SCHEMBL11714121 | 0.82 | MAOA (0.79) | MAOAMAOBNPC1RAB9AMAPT | |
| SCHEMBL4493175 | 0.82 | MAOA (0.73) | MAOAMAOBNPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160183564-A1 | USE OF A FEED COMPOSITION FOR REDUCING METHANE EMISSION IN RUMINANTS, AND OR TO IMPROVE RUMINANT PERFORMANCE | DSM IP ASSETS B.V. (NL) | 2016-06-30 | — | — | US | disclosed |
| US-20150064305-A1 | USE OF PARA NITRO AMINO DERIVATIVES IN FEED FOR REDUCING METH-ANE EMISSION IN RUMINANTS | DSM IP ASSETS B.V. (NL) | 2015-03-05 | — | — | US | disclosed |
| US-8536243-B2 | Two-component system for bone cement | TEKNIMED SAS (FR) | 2013-09-17 | — | — | US | disclosed |
| US-20110237705-A1 | TWO-COMPONENT SYSTEM FOR BONE CEMENT | TEKNIMED SAS (FR) | 2011-09-29 | — | — | US | disclosed |
| WO-2007006714-A1 | CYSTEINE PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2007-01-18 | — | — | WO | disclosed |