Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 3/20 | 0.58 |
| ▸ | MAOB | P27338 | 3/20 | 0.58 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.50 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29846220 | 0.87 | MAOA (0.68) | KDM4EMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL29736848 | 0.83 | CYP1A2 (0.60) | GAAMAPTCYP1A2CYP2C19NPC1 | |
| SCHEMBL17620760 | 0.82 | MAOA (0.58) | GAAKDM4EMAPTCYP1A2CYP3A4 | |
| SCHEMBL11647842 | 0.81 | MAOA (0.61) | KDM4EMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL15452644 | 0.81 | MAPT (0.61) | GAAKDM4EMAPTCYP1A2CYP3A4 | |
| SCHEMBL13780480 | 0.81 | MAPT (0.61) | KDM4EMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL16491982 | 0.81 | MAPT (0.68) | GAAKDM4EMAPTCYP1A2CYP3A4 | |
| SCHEMBL4028848 | 0.81 | MAPT (0.61) | GAAKDM4EMAPTCYP1A2CYP3A4 | |
| SCHEMBL28762118 | 0.81 | GAA (0.49) | GAAKDM4EMAPTCYP1A2CYP3A4 | |
| SCHEMBL17735529 | 0.80 | MAPT (0.55) | GAAMAPTCYP1A2CYP2C19ADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8536243-B2 | Two-component system for bone cement | TEKNIMED SAS (FR) | 2013-09-17 | — | — | US | disclosed |
| US-20110237705-A1 | TWO-COMPONENT SYSTEM FOR BONE CEMENT | TEKNIMED SAS (FR) | 2011-09-29 | — | — | US | disclosed |