SCHEMBL23976503

SCHEMBL23976503

CCc1sc2nc(O)nc(O)c2c1C

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.38
GAK O14976 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6015563 0.83 ABCB1 (0.42) NOTUM
SCHEMBL13982474 0.69 ABCB1 (0.39)
SCHEMBL12261730 0.68 GAK (0.43) NOTUMGAK
SCHEMBL12282112 0.66 ABCB1 (0.42) NOTUMGAK
SCHEMBL11519648 0.65 KDM4E (0.54)
SCHEMBL8197785 0.64 ALDH1A1 (0.56) NOTUM
SCHEMBL11492761 0.63 ALDH1A1 (0.54) NOTUM
SCHEMBL8188235 0.62 HPGD (0.76)
SCHEMBL11492762 0.62 ALDH1A1 (0.53)
SCHEMBL13828637 0.62 HTT (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021222483-A1 METHODS OF USE FOR PYRIMIDINES AS FERROPORTIN INHIBITORS GLOBAL BLOOD THERAPEUTICS, INC. (US) 2021-11-04 WO disclosed