Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 20/20 | 1.00 |
| ▸ | ESR1 | P03372 | 8/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 2/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 2/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.86 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20524202 | 1.00 | ESR2 (1.00) | ESR2ESR1CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL18244747 | 1.00 | ESR2 (1.00) | ESR2ESR1CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL18257874 | 0.93 | ESR2 (1.00) | ESR2ESR1CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL18257870 | 0.93 | ESR2 (1.00) | ESR2ESR1CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL18257841 | 0.93 | ESR2 (1.00) | ESR2ESR1CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL18257872 | 0.93 | ESR2 (1.00) | ESR2ESR1CYP3A4CYP2C9CYP2D6 | |
| Hydroquinone SCHEMBL408939 | 0.87 | ESR2 (0.75) | ESR2ESR1CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL1865798 | 0.84 | ESR2 (0.81) | ESR2ESR1CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL1986271 | 0.84 | ESR2 (0.81) | ESR2ESR1CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL3811445 | 0.84 | ESR2 (0.81) | ESR2ESR1CYP3A4CYP2C9CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210340155-A1 | Substituted (4-Hydroxyphenyl)Cycloalkane and (4-Hydroxyphenyl)Cycloalkene Compounds and Uses Thereof as Selective Agonists of the Estrogen Receptor Beta Isoform for Enhanced Memory Consolidation | CU Ventures, Inc. | 2021-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210340155-A1 | Substituted (4-Hydroxyphenyl)Cycloalkane and (4-Hydroxyphenyl)Cycloalkene Compounds and Uses Thereof as Selective Agonists of the Estrogen Receptor Beta Isoform for Enhanced Memory Consolidation | ESR2, GPER1, ESR1 | ESR2 1/4885ESR1 3/4885CYP3A4 1012/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.