SCHEMBL1865798

SCHEMBL1865798

Oc1ccc(C2CC2)cc1

nearest known ligand 0.81

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 20/20 0.81
ESR1 P03372 7/20 0.71
CYP3A4 P08684 2/20 0.71
CYP2C9 P11712 2/20 0.71
CYP2D6 P10635 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3809909 1.00 ESR2 (0.81) ESR2ESR1CYP3A4CYP2C9CYP2D6
SCHEMBL3811445 1.00 ESR2 (0.81) ESR2ESR1CYP3A4CYP2C9CYP2D6
SCHEMBL1986271 1.00 ESR2 (0.81) ESR2ESR1CYP3A4CYP2C9CYP2D6
SCHEMBL31574441 0.95 ESR2 (0.74) ESR2ESR1CYP3A4CYP2C9CYP2D6
SCHEMBL29156158 0.95 ESR2 (0.74) ESR2ESR1CYP3A4CYP2C9CYP2D6
SCHEMBL12840849 0.92 ESR2 (0.71) ESR2ESR1CYP3A4CYP2C9CYP2D6
SCHEMBL11871181 0.92 ESR2 (0.80) ESR2ESR1CYP3A4CYP2C9CYP2D6
SCHEMBL13955970 0.92 ESR2 (0.71) ESR2ESR1CYP3A4CYP2C9CYP2D6
SCHEMBL12840847 0.92 ESR2 (0.71) ESR2ESR1CYP3A4CYP2C9CYP2D6
SCHEMBL178486 0.90 ESR2 (1.00) ESR2ESR1CYP3A4CYP2C9CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 347 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109305892-B Synthesis method of cyclohexanol compound 中国石油化工股份有限公司 2021-09-07 CN claimed
CN-109304176-B Synthesis method of cyclohexanol compound 中国石油化工股份有限公司 2021-06-11 CN claimed
CN-111470949-A Synthesis method of cyclohexanol compound 中国石油化工股份有限公司 2020-07-31 CN claimed
CN-111470948-A Synthesis method of cyclohexanol compound 中国石油化工股份有限公司 2020-07-31 CN claimed
CN-111470950-A Synthesis method of cyclohexanol compound 中国石油化工股份有限公司 2020-07-31 CN claimed
CN-111470947-A Synthesis method of cyclohexanol compound 中国石油化工股份有限公司 2020-07-31 CN claimed
CN-109304176-A A kind of synthetic method of cyclohexanol kind compound 中国石油化工股份有限公司 2019-02-05 CN claimed
CN-109305892-A A kind of synthetic method of cyclohexanol kind compound 中国石油化工股份有限公司 2019-02-05 CN claimed
CN-101151234-B Process for producing cyclopropylphenol derivative SANKYO AGRO CO LTD 2011-06-15 CN claimed
EP-1509494-B1 AMIDOACETONITRILE COMPOUNDS AGAINST PARASITES NOVARTIS AG (CH) 2010-11-24 EP claimed
US-7629494-B2 Process for producing cyclopropylphenol derivative MITSUI CHEMICALS AGRO, INC. (JP) 2009-12-08 US claimed
US-20090054681-A1 Production Process of cyclopropylphenol derivatives SANKYO AGRO COMPANY, LIMITED (JP) 2009-02-26 US claimed
CN-101151234-A Process for producing cyclopropylphenol derivative SANKYO AGRO CO LTD (JP) 2008-03-26 CN claimed
EP-1880987-A1 PROCESS FOR PRODUCING CYCLOPROPYLPHENOL DERIVATIVE Sankyo Agro Company, Limited (JP) 2008-01-23 EP claimed
JP-11246509-A None JP disclosed
US-20260137676-A1 PIPERAZINE SUBSTITUTED PHENOL DERIVATIVE AND USE THEREOF CHENGDU MFS PHARMA. CO., LTD. (CN) 2026-05-21 US disclosed
US-20260035394-A1 1`-CYANO NUCLEOSIDE ANALOGS AND USES THEREOF GILEAD SCIENCES INC (US) 2026-02-05 US disclosed
EP-0173597-A1 Ether oxide derivatives of cyclopropyl phenols Najer, Henri (FR) 1986-03-05 EP disclosed
US-4351962-A Process for the preparation of hydroxy benzene carboxaldehydes RHONE POULENC INC. (US) 1982-09-28 US disclosed
US-4054667-A METAMORPHOSIS INHIBITION STAUFFER CHEMICAL COMPANY (US) 1977-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054681-A1 Production Process of cyclopropylphenol derivatives CBR3, CYP4X1, CYP4A11 ESR2 1931/4885ESR1 1620/4885CYP3A4 8/4885
US-20260035394-A1 1`-CYANO NUCLEOSIDE ANALOGS AND USES THEREOF PNP, SLC28A1, SLC29A1 ESR2 4797/4885ESR1 4845/4885CYP3A4 1360/4885
US-20260137676-A1 PIPERAZINE SUBSTITUTED PHENOL DERIVATIVE AND USE THEREOF CNR1, SIGMAR1, CBR1 ESR2 1784/4885ESR1 1654/4885CYP3A4 8/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.