Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.57 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.56 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.54 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.51 |
| ▸ | HTR6 | P50406 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | PI4KA | P42356 | 1/20 | 0.41 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.41 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.41 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30291239 | 1.00 | HTR2C (0.57) | HTR2CPDE10AHRH4TLR7HTR6 | |
| SCHEMBL23977316 | 0.87 | HTR2C (0.55) | HTR2CPDE10AHRH4TLR7HTR6 | |
| SCHEMBL30225357 | 0.87 | HTR2C (0.55) | HTR2CPDE10AHRH4TLR7HTR6 | |
| SCHEMBL30225539 | 0.86 | HRH4 (0.73) | HTR2CPDE10AHRH4TLR7ALDH1A1 | |
| SCHEMBL23977352 | 0.86 | HRH4 (0.73) | HTR2CPDE10AHRH4TLR7ALDH1A1 | |
| SCHEMBL23977294 | 0.78 | HDAC6 (0.58) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL23977295 | 0.77 | HRH4 (0.49) | PDE10AHRH4ALDH1A1POLBHPGD | |
| SCHEMBL30225385 | 0.77 | ADORA2A (0.68) | ALDH1A1ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL23977384 | 0.77 | ADORA2A (0.68) | ALDH1A1ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL23977241 | 0.76 | HTR2C (0.46) | HTR2CTLR7PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219964-A1 | ANTIBACTERIAL AND ANTIFUNGAL PLEUROMUTILIN CONJUGATES | SYDDANSK UNIVERSITET (DK) | 2023-07-13 | — | — | US | disclosed |
| US-20230219964-A1 | ANTIBACTERIAL AND ANTIFUNGAL PLEUROMUTILIN CONJUGATES | SYDDANSK UNIVERSITET (DK) | 2023-07-13 | — | — | US | disclosed |
| WO-2021219813-A1 | ANTIBACTERIAL AND ANTIFUNGAL PLEUROMUTILIN CONJUGATES | SYDDANSK UNIVERSITET (DK) | 2021-11-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219964-A1 | ANTIBACTERIAL AND ANTIFUNGAL PLEUROMUTILIN CONJUGATES | HDAC6, Q6ZSR9, MON2 | HTR2C 4130/4885PDE10A 4588/4885HRH4 2797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.