Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ADK | P55263 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28977406 | 1.00 | HTR2C (0.46) | HTR2CTLR7PIK3CDHTTTDP1 | |
| SCHEMBL30225391 | 1.00 | HTR2C (0.46) | HTR2CTLR7PIK3CDHTTTDP1 | |
| SCHEMBL30225397 | 0.83 | TDP1 (0.38) | PIK3CDTDP1 | |
| SCHEMBL28977404 | 0.79 | CNR1 (0.44) | PIK3CDHTTTDP1ADK | |
| SCHEMBL23977344 | 0.79 | CNR1 (0.44) | PIK3CDHTTTDP1ADK | |
| SCHEMBL30291196 | 0.79 | HTR2C (0.43) | HTR2CTLR7PIK3CDHTTTDP1 | |
| SCHEMBL23977342 | 0.78 | ADORA2A (0.57) | PIK3CD | |
| SCHEMBL30291134 | 0.78 | ADORA2A (0.57) | PIK3CD | |
| SCHEMBL28977403 | 0.78 | ADORA2A (0.57) | PIK3CD | |
| SCHEMBL23977303 | 0.76 | HTR2C (0.57) | HTR2CTLR7PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219964-A1 | ANTIBACTERIAL AND ANTIFUNGAL PLEUROMUTILIN CONJUGATES | SYDDANSK UNIVERSITET (DK) | 2023-07-13 | — | — | US | disclosed |
| US-20230219964-A1 | ANTIBACTERIAL AND ANTIFUNGAL PLEUROMUTILIN CONJUGATES | SYDDANSK UNIVERSITET (DK) | 2023-07-13 | — | — | US | disclosed |
| CN-115720579-A | Antibacterial and antifungal pleuromutilin conjugates | 赛丹思科大学 | 2023-02-28 | — | — | CN | disclosed |
| WO-2021219813-A1 | ANTIBACTERIAL AND ANTIFUNGAL PLEUROMUTILIN CONJUGATES | SYDDANSK UNIVERSITET (DK) | 2021-11-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219964-A1 | ANTIBACTERIAL AND ANTIFUNGAL PLEUROMUTILIN CONJUGATES | HDAC6, Q6ZSR9, MON2 | HTR2C 4130/4885TLR7 1514/4885PIK3CD 2403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.