Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 10/20 | 0.57 |
| ▸ | PI4KA | P42356 | 3/20 | 0.57 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.57 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.57 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.57 |
| ▸ | NSD2 | O96028 | 2/20 | 0.56 |
| ▸ | NSD3 | Q9BZ95 | 2/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.50 |
| ▸ | AHCY | P23526 | 5/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30225464 | 1.00 | ADORA2A (0.57) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL30225408 | 0.82 | ADORA2A (0.54) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL23977338 | 0.82 | ADORA2A (0.54) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL23977306 | 0.78 | AHCY (0.58) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL30225389 | 0.78 | AHCY (0.58) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL11813776 | 0.75 | ADORA2A (0.63) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL11809827 | 0.74 | ADORA2A (0.66) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| 9-Benzyl-9H-Adenine SCHEMBL104932 | 0.73 | ADORA2A (1.00) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL11222112 | 0.72 | ADORA2A (0.80) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL29093660 | 0.72 | NSD3 (1.00) | ADORA2ANSD2NSD3ADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219964-A1 | ANTIBACTERIAL AND ANTIFUNGAL PLEUROMUTILIN CONJUGATES | SYDDANSK UNIVERSITET (DK) | 2023-07-13 | — | — | US | disclosed |
| US-20230219964-A1 | ANTIBACTERIAL AND ANTIFUNGAL PLEUROMUTILIN CONJUGATES | SYDDANSK UNIVERSITET (DK) | 2023-07-13 | — | — | US | disclosed |
| CN-115720579-A | Antibacterial and antifungal pleuromutilin conjugates | 赛丹思科大学 | 2023-02-28 | — | — | CN | disclosed |
| WO-2021219813-A1 | ANTIBACTERIAL AND ANTIFUNGAL PLEUROMUTILIN CONJUGATES | SYDDANSK UNIVERSITET (DK) | 2021-11-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219964-A1 | ANTIBACTERIAL AND ANTIFUNGAL PLEUROMUTILIN CONJUGATES | HDAC6, Q6ZSR9, MON2 | ADORA2A 4156/4885PI4KA 1564/4885PI4K2B 1170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.