Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.52 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.50 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2706726 | 0.87 | GRN (0.57) | NR3C2LMNANPSR1TRPV1 | |
| SCHEMBL21462630 | 0.87 | KLKB1 (0.59) | NR3C2PTGS2PTGS1KLKB1LMNA | |
| SCHEMBL27584609 | 0.87 | KLKB1 (0.61) | NR3C2PTGS2PTGS1KLKB1SCN9A | |
| SCHEMBL22122090 | 0.85 | PTGS2 (0.57) | PTGS2PTGS1KLKB1PDPK1 | |
| SCHEMBL15428613 | 0.79 | MAPT (0.54) | PTGS2LMNA | |
| SCHEMBL15347126 | 0.79 | PTGS2 (0.68) | NR3C2PTGS2PTGS1PDPK1 | |
| SCHEMBL22417059 | 0.78 | KLKB1 (0.58) | PTGS2PTGS1KLKB1SCN9A | |
| SCHEMBL15347202 | 0.78 | PTGS2 (0.67) | NR3C2PTGS2PTGS1PDPK1 | |
| SCHEMBL1013645 | 0.76 | PTGS2 (0.55) | NR3C2PTGS2PTGS1LMNA | |
| SCHEMBL17064344 | 0.76 | KLKB1 (0.84) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3904350-A1 | N-(CYCLOPROPYLMETHYL)-5-(METHYLSULFONYL)-N-{1-[1-(PYRIMIDIN-2-YL)-1H-1,2,4-TRIAZOL-5-YL]ETHYL}BENZAMIDE DERIVATIVES AND THE CORRESPONDING PYRIDINE-CARBOXAMIDE DERIVATIVES AS PESTICIDES | Bayer Aktiengesellschaft (DE) | 2021-11-03 | — | — | EP | disclosed |