Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.52 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.52 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20333397 | 0.86 | HRH3 (0.46) | CARM1PRMT6PRMT8CA12CA1 | |
| SCHEMBL4569287 | 0.84 | CARM1 (0.58) | CARM1PRMT6PRMT8CA12CA1 | |
| SCHEMBL5226705 | 0.82 | CARM1 (0.56) | CARM1PRMT6PRMT8CA12CA1 | |
| SCHEMBL2156090 | 0.82 | CARM1 (0.56) | CARM1PRMT6PRMT8CA12CA1 | |
| SCHEMBL13787914 | 0.79 | CARM1 (0.52) | CARM1PRMT6PRMT8CA12CA1 | |
| SCHEMBL9090552 | 0.78 | CARM1 (0.52) | CARM1PRMT6PRMT8CA12CA1 | |
| SCHEMBL18782445 | 0.77 | CARM1 (0.50) | CARM1PRMT6PRMT8CA12CA1 | |
| SCHEMBL10574951 | 0.77 | CARM1 (0.50) | CARM1PRMT6PRMT8CA12CA1 | |
| SCHEMBL25736046 | 0.77 | CARM1 (0.48) | CARM1PRMT6PRMT8CA12CA1 | |
| SCHEMBL20332945 | 0.75 | CARM1 (0.48) | CARM1PRMT6PRMT8CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021219091-A2 | QUINOXALINONE DERIVATIVE AS IRREVERSIBLE INHIBITOR OF KRAS G12C MUTANT PROTEIN | 北京泰德制药股份有限公司 (CN) | 2021-11-04 | — | — | WO | disclosed |