SCHEMBL2156090

SCHEMBL2156090

CC(C)NCCN1CCCCC1

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 1/20 0.56
PRMT6 Q96LA8 1/20 0.56
PRMT8 Q9NR22 1/20 0.56
HRH3 Q9Y5N1 1/20 0.44
CA12 O43570 3/20 0.44
CA1 P00915 3/20 0.44
CA2 P00918 3/20 0.44
CA9 Q16790 3/20 0.44
NPC1 O15118 1/20 0.42
ALDH1A1 P00352 3/20 0.40
KDM4E B2RXH2 1/20 0.40
DPP7 Q9UHL4 1/20 0.37
PSMB1 P20618 1/20 0.37
PSMB5 P28074 1/20 0.37
MAPT P10636 2/20 0.37
POLB P06746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5226705 1.00 CARM1 (0.56) CARM1PRMT6PRMT8HRH3CA12
SCHEMBL4569287 0.98 CARM1 (0.58) CARM1PRMT6PRMT8HRH3CA12
SCHEMBL13787914 0.93 CARM1 (0.52) CARM1PRMT6PRMT8HRH3CA12
SCHEMBL25736046 0.90 CARM1 (0.48) CARM1PRMT6PRMT8CA12CA1
SCHEMBL12309176 0.86 HRH3 (0.52) CARM1PRMT6PRMT8HRH3MAPT
SCHEMBL18568453 0.86 HRH3 (0.52) CARM1PRMT6PRMT8HRH3MAPT
SCHEMBL16311941 0.85 HRH3 (0.56) CARM1PRMT6PRMT8HRH3MAPT
SCHEMBL10574951 0.85 CARM1 (0.50) CARM1PRMT6PRMT8HRH3CA12
SCHEMBL18782445 0.85 CARM1 (0.50) CARM1PRMT6PRMT8HRH3CA12
SCHEMBL8258583 0.84 CARM1 (0.48) CARM1PRMT6PRMT8HRH3MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 180 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11136434-B2 Polyamines, synthesis method thereof and use thereof for the selective elimination of H2S from a gaseous effluent comprising CO2 IFP Energies Nouvelles (FR) 2021-10-05 US claimed
CN-108602952-B Novel polyamines, method for their synthesis and their use for the removal of CO from a gas containing atmosphere2Selective removal of H from the gaseous effluent of2Use of S IFP 新能源公司 2021-03-12 CN claimed
US-10710021-B2 Polyamines, synthesis process thereof and use of same for the selective elimination of H2S from a gaseous effluent comprising CO2 IFP Energies Nouvelles (FR) 2020-07-14 US claimed
US-20200148824-A1 NOVEL POLYAMINES, SYNTHESIS METHOD THEREOF AND USE THEREOF FOR THE SELECTIVE ELIMINATION OF H2S FROM A GASEOUS EFFLUENT COMPRISING CO2 IFP Energies Nouvelles (FR) 2020-05-14 US claimed
EP-3645605-A1 NOVEL POLYAMINES, SYNTHESIS METHOD THEREOF AND USE THEREOF FOR THE SELECTIVE ELEMINATION OF H2S FROM A GASEOUS EFFLUENT COMPRISING C02 IFP Energies nouvelles (FR) 2020-05-06 EP claimed
EP-3397671-B1 NOVEL POLYAMINES, SYNTHESIS PROCESS THEREOF AND USE OF SAME FOR THE SELECTIVE ELIMINATION OF H2S FROM A GASEOUS EFFLUENT COMPRISING CO2 IFP ENERGIES NOW (FR) 2020-02-12 EP claimed
US-20180369743-A1 NOVEL POLYAMINES, SYNTHESIS PROCESS THEREOF AND USE OF SAME FOR THE SELECTIVE ELIMINATION OF H2S FROM A GASEOUS EFFLUENT COMPRISING CO2 IFP Energies Nouvelles (FR) 2018-12-27 US claimed
EP-3397671-A1 NOVEL POLYAMINES, SYNTHESIS PROCESS THEREOF AND USE OF SAME FOR THE SELECTIVE ELIMINATION OF H2S FROM A GASEOUS EFFLUENT COMPRISING CO2 IFP Energies nouvelles (FR) 2018-11-07 EP claimed
CN-108602952-A Novel polyamines, a process for their synthesis and their use for the selective removal of H2S from gaseous effluents containing CO2 IFP 新能源公司 2018-09-28 CN claimed
US-20130011314-A1 METHOD OF REMOVING ACID COMPOUNDS FROM A GASEOUS EFFLUENT WITH AN ABSORBENT SOLUTION BASED ON I, II/III DIAMINES IFP Energies Nouvelles (FR) 2013-01-10 US claimed
WO-2024123633-A1 LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF RECODE THERAPEUTICS, INC. (US) 2024-06-13 WO disclosed
US-20240025922-A1 TETRAHYDROPYRIDO[3,4-d]PYRIMIDINES AS HPK1 INHIBITORS MERCK HEALTHCARE KGAA (DE) 2024-01-25 US disclosed
US-20240018150-A1 SMALL MOLECULAR INHIBITOR AGAINST BTK AND/OR BTK C481S AND USE THEREOF ARROMAX PHARMATECH CO., LTD. (CN) 2024-01-18 US disclosed
US-11873291-B2 Quinoline cGAS antagonist compounds IMMUNESENSOR THERAPEUTICS, INC. (US) 2024-01-16 US disclosed
US-20230399303-A1 Macrophage Migration Inhibitory Factor Inhibitors, and Methods of Making and Using Same UNIV YALE (US) 2023-12-14 US disclosed
US-4146558-A Azo dyestuff intermediate nitro- or aminobenzenes ring-substituted by a quaternized amine alkyl or amino-alkoxy group STERLING DRUG INC. (US) 1979-03-27 US disclosed
US-4103092-A Water-soluble quaternary ammonium non-heterocyclic azo dyestuffs STERLING DRUG INC. (US) 1978-07-25 US disclosed
US-4065500-A Water-soluble quaternary ammonium azo dyestuffs STERLING DRUG INC. (US) 1977-12-27 US disclosed
US-3996282-A Water-soluble quaternary ammonium dyestuffs STERLING DRUG INC. (US) 1976-12-07 US disclosed
US-3935182-A Water-soluble quaternary ammonium heterocyclic azo dyestuffs STERLING DRUG INC. (US) 1976-01-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11873291-B2 Quinoline cGAS antagonist compounds CGAS, GLS2, GLS CARM1 4298/4885PRMT6 3040/4885PRMT8 2620/4885
US-20240025922-A1 TETRAHYDROPYRIDO[3,4-d]PYRIMIDINES AS HPK1 INHIBITORS PDXK, DTYMK, HIPK1 CARM1 3846/4885PRMT6 2289/4885PRMT8 2700/4885
US-20240018150-A1 SMALL MOLECULAR INHIBITOR AGAINST BTK AND/OR BTK C481S AND USE THEREOF BTK, SYK, LCK CARM1 1198/4885PRMT6 2081/4885PRMT8 2199/4885
US-20230399303-A1 Macrophage Migration Inhibitory Factor Inhibitors, and Methods of Making and Using Same MIF, MMP12, METAP1 CARM1 1063/4885PRMT6 217/4885PRMT8 211/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.