Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 11/20 | 0.50 |
| ▸ | NPY1R | P25929 | 6/20 | 0.50 |
| ▸ | NPY2R | P49146 | 4/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.50 |
| ▸ | KISS1R | Q969F8 | 6/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17132197 | 1.00 | NPY4R (0.50) | NPY4RNPY1RNPY2RNPY5RKISS1R | |
| SCHEMBL19249630 | 1.00 | NPY4R (0.50) | NPY4RNPY1RNPY2RNPY5RKISS1R | |
| SCHEMBL18413061 | 1.00 | NPY4R (0.50) | NPY4RNPY1RNPY2RNPY5RKISS1R | |
| SCHEMBL4451321 | 1.00 | NPY4R (0.50) | NPY4RNPY1RNPY2RNPY5RKISS1R | |
| SCHEMBL29372181 | 0.86 | NPY1R (0.54) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL23977925 | 0.85 | MMP9 (0.48) | KISS1ROPRD1MMP9MMP8KLKB1 | |
| SCHEMBL4451327 | 0.84 | NPY4R (0.45) | NPY4RNPY1RNPY2RNPY5RKISS1R | |
| SCHEMBL29652154 | 0.82 | NPY4R (0.58) | NPY4RNPY1RNPY2RNPY5RKISS1R | |
| SCHEMBL29652137 | 0.82 | NPY4R (0.58) | NPY4RNPY1RNPY2RNPY5RKISS1R | |
| SCHEMBL23142771 | 0.82 | NPY4R (0.58) | NPY4RNPY1RNPY2RNPY5RKISS1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222886-A1 | COMPOSITIONS AND METHODS TO TREAT POLYCYSTIC KIDNEY DISEASE | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2021-11-04 | — | — | WO | disclosed |