Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GRM5 | P41594 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26453317 | 0.71 | RXRA (0.33) | MAPK1GAAMEN1KMT2AGRM5 | |
| SCHEMBL15832227 | 0.69 | CCR1 (0.43) | MEN1KMT2AGRM5RAB9AASIC3 | |
| SCHEMBL22811906 | 0.68 | CCR1 (0.41) | MEN1KMT2AGRM5RAB9AASIC3 | |
| SCHEMBL12093748 | 0.67 | GRM5 (0.47) | MEN1KMT2AGRM5RAB9ACCR1 | |
| SCHEMBL30072637 | 0.67 | GRM5 (0.47) | MEN1KMT2AGRM5RAB9ACCR1 | |
| SCHEMBL23977885 | 0.67 | RXRA (0.32) | GRM5CCR1CCR8CCR5 | |
| SCHEMBL13680498 | 0.66 | CCR1 (0.43) | MAPK1GAAMEN1KMT2AGRM5 | |
| SCHEMBL14897540 | 0.65 | CCR1 (0.39) | MEN1KMT2AGRM5RAB9ACCR1 | |
| SCHEMBL31424083 | 0.65 | KMT2A (0.46) | MAPK1MEN1KMT2AGRM5RAB9A | |
| SCHEMBL128705 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021219594-A1 | SPIROUREA DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2021-11-04 | — | — | WO | disclosed |