Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CXCR5 | P32302 | 5/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.30 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23965633 | 0.80 | SMN1; SMN2 (0.33) | CYP1A2CYP3A4TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL23977989 | 0.78 | KDM4E (0.34) | CYP3A4SMN1; SMN2ALDH1A1KMT2ACXCR5 | |
| SCHEMBL23969498 | 0.74 | CYP3A4 (0.38) | CYP1A2CYP3A4TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL23965575 | 0.71 | PPARG (0.43) | — | |
| SCHEMBL23967941 | 0.71 | CXCR5 (0.44) | TSHRCXCR5 | |
| SCHEMBL23965570 | 0.68 | CYP1A2 (0.34) | CYP1A2CYP3A4TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL23965716 | 0.67 | GAA (0.40) | CYP1A2CYP3A4TSHRALDH1A1L3MBTL1 | |
| SCHEMBL23965593 | 0.65 | KDM4E (0.33) | CYP3A4TSHRSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL23965579 | 0.64 | CYP3A4 (0.36) | CYP1A2CYP3A4TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL23965618 | 0.64 | CYP3A4 (0.33) | CYP3A4ALDH1A1KMT2ACXCR5L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3903581-A1 | USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS I | BASF SE (DE) | 2021-11-03 | — | — | EP | disclosed |