Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1632089 | 0.78 | POLB (0.30) | POLB | |
| SCHEMBL14463511 | 0.77 | ALDH1A1 (0.49) | ALDH1A1KDM4EGAAMAPTSMN1; SMN2 | |
| SCHEMBL5237110 | 0.77 | ALDH1A1 (0.49) | ALDH1A1KDM4EGAAMAPTSMN1; SMN2 | |
| SCHEMBL25735070 | 0.76 | ALDH1A1 (0.49) | ALDH1A1KDM4EGAAMAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5240143 | 0.75 | ALDH1A1 (0.47) | ALDH1A1KDM4EGAAMAPTSMN1; SMN2 | |
| SCHEMBL12994836 | 0.75 | ALDH1A1 (0.47) | ALDH1A1KDM4EGAAMAPTSMN1; SMN2 | |
| SCHEMBL16378120 | 0.75 | ALDH1A1 (0.47) | ALDH1A1KDM4EGAAMAPTSMN1; SMN2 | |
| SCHEMBL23894828 | 0.74 | CYP1A2 (0.43) | ALDH1A1KDM4EGAAMAPTSMN1; SMN2 | |
| SCHEMBL13317748 | 0.72 | KMT2A (0.53) | ALDH1A1KDM4EGAAMAPTSMN1; SMN2 | |
| SCHEMBL9906480 | 0.72 | GAA (0.50) | ALDH1A1KDM4EGAAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222777-A1 | CD33 LIGANDS SUITABLE FOR INCORPORATION INTO CARRIERS | MAGNANI JOHN L (US) | 2021-11-04 | — | — | WO | disclosed |