Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.51 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.47 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.47 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23978834 | 0.89 | KCNQ2 (0.54) | KCNQ2MEN1KMT2AALDH1A1CSNK1D | |
| SCHEMBL30336898 | 0.89 | KCNQ2 (0.54) | KCNQ2MEN1KMT2AALDH1A1CSNK1D | |
| SCHEMBL23978894 | 0.88 | KCNQ2 (0.54) | KCNQ2MEN1KMT2AALDH1A1CSNK1D | |
| SCHEMBL24803414 | 0.82 | KCNQ2 (0.47) | KCNQ2MEN1KMT2AALDH1A1CSNK1D | |
| SCHEMBL26107107 | 0.78 | KCNQ2 (0.44) | KCNQ2MEN1KMT2AALDH1A1CACNA1G | |
| SCHEMBL23978813 | 0.78 | KCNQ2 (0.44) | KCNQ2MEN1KMT2AALDH1A1CACNA1G | |
| SCHEMBL30279468 | 0.78 | KCNQ2 (0.44) | KCNQ2MEN1KMT2AALDH1A1CACNA1G | |
| SCHEMBL6581781 | 0.76 | KCNQ2 (0.60) | KCNQ2MEN1KMT2AALDH1A1CSNK1D | |
| SCHEMBL23978639 | 0.75 | KCNQ2 (0.42) | KCNQ2MEN1KMT2AALDH1A1CSNK1D | |
| SCHEMBL8279071 | 0.75 | HPGD (0.57) | KCNQ2MEN1KMT2AALDH1A1MAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222789-A1 | INHIBITORS OF ALPHA 2 BETA 1 INTEGRIN AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-11-04 | — | — | WO | disclosed |