Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 4/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PYGL | P06737 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23978981 | 0.84 | POLB (0.48) | KCNQ2MAPK8MEN1KMT2APOLB | |
| SCHEMBL23978644 | 0.84 | HPGD (0.45) | MEN1KMT2AALDH1A1POLB | |
| SCHEMBL26494992 | 0.82 | USP2 (0.41) | KCNQ2ALDH1A1CTSDEPHX2 | |
| SCHEMBL30279388 | 0.82 | USP2 (0.41) | KCNQ2ALDH1A1CTSDEPHX2 | |
| SCHEMBL24803335 | 0.82 | USP2 (0.41) | KCNQ2ALDH1A1CTSDEPHX2 | |
| SCHEMBL30279468 | 0.81 | KCNQ2 (0.44) | KCNQ2MAPK8MEN1KMT2AALDH1A1 | |
| SCHEMBL23978813 | 0.81 | KCNQ2 (0.44) | KCNQ2MAPK8MEN1KMT2AALDH1A1 | |
| SCHEMBL26107107 | 0.81 | KCNQ2 (0.44) | KCNQ2MAPK8MEN1KMT2AALDH1A1 | |
| SCHEMBL30279367 | 0.80 | CTSL (0.45) | KCNQ2MEN1KMT2AALDH1A1ITGB1 | |
| SCHEMBL23978812 | 0.80 | CTSL (0.45) | KCNQ2MEN1KMT2AALDH1A1ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222789-A1 | INHIBITORS OF ALPHA 2 BETA 1 INTEGRIN AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-11-04 | — | — | WO | disclosed |