Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 3/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TAOK1 | Q7L7X3 | 4/20 | 0.34 |
| ▸ | TAOK3 | Q9H2K8 | 4/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23978691 | 0.94 | PRMT5 (0.36) | PRMT5USP2MEN1KMT2A | |
| SCHEMBL24804669 | 0.87 | USP2 (0.44) | PRMT5USP2TSHRLMNAKMT2A | |
| SCHEMBL30279436 | 0.87 | USP2 (0.44) | PRMT5USP2TSHRLMNAKMT2A | |
| SCHEMBL24803328 | 0.87 | USP2 (0.44) | PRMT5USP2TSHRLMNAKMT2A | |
| SCHEMBL23979052 | 0.84 | ITGB2 (0.39) | PRMT5MEN1KMT2A | |
| SCHEMBL26495894 | 0.84 | USP2 (0.45) | USP2TSHRMEN1LMNAKMT2A | |
| SCHEMBL30279420 | 0.84 | USP2 (0.45) | USP2TSHRMEN1LMNAKMT2A | |
| SCHEMBL24804667 | 0.84 | USP2 (0.45) | USP2TSHRMEN1LMNAKMT2A | |
| SCHEMBL23979031 | 0.78 | EPHX2 (0.42) | PRMT5MTNR1AMTNR1BMEN1LMNA | |
| SCHEMBL23978978 | 0.78 | EPHX2 (0.42) | PRMT5MTNR1AMTNR1BMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222789-A1 | INHIBITORS OF ALPHA 2 BETA 1 INTEGRIN AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-11-04 | — | — | WO | disclosed |