Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 7/20 | 0.39 |
| ▸ | ICAM1 | P05362 | 7/20 | 0.39 |
| ▸ | ITGAL | P20701 | 7/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 6/20 | 0.39 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 6/20 | 0.38 |
| ▸ | ITGAV | P06756 | 4/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23978691 | 0.90 | PRMT5 (0.36) | ITGB1ITGA5PRMT5MEN1KMT2A | |
| SCHEMBL23978677 | 0.84 | PRMT5 (0.39) | PRMT5MEN1KMT2A | |
| SCHEMBL23978938 | 0.83 | EPHX2 (0.43) | ITGB2ICAM1ITGALPRMT5MEN1 | |
| SCHEMBL26106493 | 0.83 | EPHX2 (0.43) | ITGB2ICAM1ITGALPRMT5MEN1 | |
| SCHEMBL23978584 | 0.83 | EPHX2 (0.43) | ITGB2ICAM1ITGALPRMT5MEN1 | |
| SCHEMBL30279419 | 0.83 | EPHX2 (0.43) | ITGB2ICAM1ITGALPRMT5MEN1 | |
| SCHEMBL23978978 | 0.80 | EPHX2 (0.42) | ITGB2ICAM1ITGALPRMT5MEN1 | |
| SCHEMBL30279418 | 0.80 | EPHX2 (0.42) | ITGB2ICAM1ITGALPRMT5MEN1 | |
| SCHEMBL23979031 | 0.80 | EPHX2 (0.42) | ITGB2ICAM1ITGALPRMT5MEN1 | |
| SCHEMBL26106656 | 0.80 | EPHX2 (0.42) | ITGB2ICAM1ITGALPRMT5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222789-A1 | INHIBITORS OF ALPHA 2 BETA 1 INTEGRIN AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-11-04 | — | — | WO | disclosed |