Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 2/20 | 0.36 |
| ▸ | CKS1B | P61024 | 2/20 | 0.36 |
| ▸ | SKP1 | P63208 | 2/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.35 |
| ▸ | STS | P08842 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | F13A1 | P00488 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21722183 | 0.75 | GBA1 (0.44) | CXCR2GBA1CKS1BSKP1SKP2 | |
| SCHEMBL23979677 | 0.74 | CXCR2 (0.39) | CXCR2GBA1CKS1BSKP1SKP2 | |
| SCHEMBL19949022 | 0.72 | CCNA2 (0.41) | CXCR2GBA1CKS1BSKP1SKP2 | |
| SCHEMBL25771136 | 0.72 | CXCR2 (0.38) | CXCR2GBA1CKS1BSKP1SKP2 | |
| SCHEMBL23979654 | 0.72 | GBA1 (0.39) | CXCR2GBA1CKS1BSKP1SKP2 | |
| SCHEMBL19947629 | 0.72 | ACHE (0.44) | GBA1CKS1BSKP1SKP2KIT | |
| SCHEMBL19964211 | 0.71 | MTOR (0.45) | GBA1CCNA2CDK2MAPTALDH1A1 | |
| SCHEMBL30177806 | 0.69 | CCNA2 (0.39) | CXCR2GBA1CKS1BSKP1SKP2 | |
| SCHEMBL21722244 | 0.69 | CCNA2 (0.39) | CXCR2GBA1CKS1BSKP1SKP2 | |
| SCHEMBL19616489 | 0.69 | TMEM97 (0.46) | MEN1KMT2ATLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021219072-A1 | PREPARATION AND APPLICATION METHOD OF HETEROCYCLIC COMPOUND AS KRAS INHIBITOR | 上海科州药物研发有限公司 (CN) | 2021-11-04 | — | — | WO | disclosed |