Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13290568 | 0.86 | CHRNA7 (0.46) | CHRNA7KDM4EALDH1A1MAPTPKM | |
| SCHEMBL1106901 | 0.86 | — | — | |
| SCHEMBL13290580 | 0.86 | CHRNA7 (0.46) | CHRNA7KDM4EALDH1A1MAPTPKM | |
| SCHEMBL6660188 | 0.86 | CHRNA7 (0.46) | CHRNA7KDM4EALDH1A1MAPTPKM | |
| SCHEMBL13290572 | 0.86 | CHRNA7 (0.46) | CHRNA7KDM4EALDH1A1MAPTPKM | |
| SCHEMBL681912 | 0.86 | CHRNA7 (0.46) | CHRNA7KDM4EALDH1A1MAPTPKM | |
| SCHEMBL6658443 | 0.82 | CHRNA7 (0.43) | CHRNA7KDM4EALDH1A1MAPTPKM | |
| Hydrochloric Acid SCHEMBL6663708 | 0.79 | CHRNA7 (0.42) | CHRNA7KDM4EALDH1A1MAPTPKM | |
| SCHEMBL13290564 | 0.76 | CHRNA7 (0.40) | CHRNA7KDM4EALDH1A1MAPTPKM | |
| SCHEMBL840810 | 0.76 | CHRNA7 (0.40) | CHRNA7KDM4EALDH1A1MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023173083-A1 | TETRAHYDROINDOLE DERIVATIVES AS EGFR AND/OR HER2 INHIBTORS USEFUL FOR THE TREATMENT OF CANCER | SCORPION THERAPEUTICS, INC. (US) | 2023-09-14 | — | — | WO | disclosed |
| WO-2022150543-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2022-07-14 | — | — | WO | disclosed |
| WO-2022094271-A1 | METHODS FOR TREATING CANCER | SCORPION THERAPEUTICS, INC. (US) | 2022-05-05 | — | — | WO | disclosed |
| WO-2021219019-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO, INC. (US) | 2021-11-04 | — | — | WO | disclosed |