Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 7/20 | 0.43 |
| ▸ | STS | P08842 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 3/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23980815 | 0.87 | LTA4H (0.39) | MEN1KMT2ALTA4H | |
| SCHEMBL23980778 | 0.86 | CYP3A4 (0.42) | MEN1KMT2ASTSHTTUTS2R | |
| SCHEMBL30564498 | 0.86 | CYP3A4 (0.42) | MEN1KMT2ASTSHTTUTS2R | |
| SCHEMBL25403420 | 0.85 | MEN1 (0.43) | MEN1KMT2ASTSSMN1; SMN2NPSR1 | |
| SCHEMBL27288015 | 0.85 | MEN1 (0.43) | MEN1KMT2ASTSSMN1; SMN2NPSR1 | |
| SCHEMBL23980870 | 0.85 | MEN1 (0.43) | MEN1KMT2ASTSSMN1; SMN2NPSR1 | |
| SCHEMBL25406089 | 0.80 | PDK4 (0.50) | MEN1KMT2A | |
| SCHEMBL27288009 | 0.80 | PDK4 (0.50) | MEN1KMT2A | |
| SCHEMBL23980819 | 0.80 | PDK4 (0.50) | MEN1KMT2A | |
| SCHEMBL24186580 | 0.79 | CYP3A4 (0.42) | MEN1KMT2ASTSHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021219019-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO, INC. (US) | 2021-11-04 | — | — | WO | disclosed |