Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 19/20 | 1.00 |
| ▸ | MAOB | P27338 | 12/20 | 1.00 |
| ▸ | MAOA | P21397 | 13/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2755978 | 1.00 | KDM1A (1.00) | KDM1AMAOBMAOA | |
| SCHEMBL20178941 | 1.00 | KDM1A (1.00) | KDM1AMAOBMAOA | |
| SCHEMBL239814 | 1.00 | KDM1A (1.00) | KDM1AMAOBMAOA | |
| SCHEMBL31744990 | 1.00 | KDM1A (1.00) | KDM1AMAOBMAOA | |
| SCHEMBL20598055 | 1.00 | KDM1A (1.00) | KDM1AMAOBMAOA | |
| SCHEMBL25997507 | 0.81 | KDM1A (0.68) | KDM1AMAOBMAOA | |
| SCHEMBL2755987 | 0.80 | KDM1A (1.00) | KDM1AMAOBMAOA | |
| SCHEMBL240169 | 0.80 | KDM1A (1.00) | KDM1AMAOBMAOA | |
| SCHEMBL2755988 | 0.80 | KDM1A (1.00) | KDM1AMAOBMAOA | |
| SCHEMBL239891 | 0.80 | KDM1A (1.00) | KDM1AMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250017933-A1 | CANCER TREATMENT USING LSD1 INHIBITORS AND PLK1 INHIBITORS | CARDIFF ONCOLOGY, INC. | 2025-01-16 | — | — | US | claimed |
| WO-2023091932-A1 | CANCER TREATMENT USING LSD1 INHIBITORS AND PLK1 INHIBITORS | CARDIFF ONCOLOGY, INC. (US) | 2023-05-25 | — | — | WO | claimed |
| US-20200054578-A1 | LSD1 INHIBITORS AS SKELETAL MUSCLE HYPERTROPHY INDUCERS | CYTOO (FR) | 2020-02-20 | — | — | US | claimed |
| EP-3541372-A1 | LSD1 INHIBITORS AS SKELETAL MUSCLE HYPERTROPHY INDUCERS | Cytoo (FR) | 2019-09-25 | — | — | EP | claimed |
| WO-2018091691-A1 | LSD1 INHIBITORS AS SKELETAL MUSCLE HYPERTROPHY INDUCERS | CYTOO (FR) | 2018-05-24 | — | — | WO | claimed |
| US-9616058-B2 | Potent selective LSD1 inhibitors and dual LSD1/MAO-B inhibitors for antiviral use | ORYZON GENOMICS, S.A. (ES) | 2017-04-11 | — | — | US | claimed |
| US-20160045456-A1 | PHENYLCYCLOPROPYLAMINE DERIVATIVES AND THEIR MEDICAL USE | ORYZON GENOMICS S.A. (ES) | 2016-02-18 | — | — | US | claimed |
| US-8993808-B2 | Phenylcyclopropylamine derivatives and their medical use | ORYZON GENOMICS, S.A. (ES) | 2015-03-31 | — | — | US | claimed |
| US-20120004262-A1 | PHENYLCYCLOPROPYLAMINE DERIVATIVES AND THEIR MEDICAL USE | ORYZON GENOMICS, S.A. (ES) | 2012-01-05 | — | — | US | claimed |
| EP-2389362-A1 | PHENYLCYCLOPROPYLAMINE DERIVATIVES AND THEIR MEDICAL USE | Oryzon Genomics, S.A. (ES) | 2011-11-30 | — | — | EP | claimed |
| US-20110252680-A1 | Surface mounted frame arrangement | ROSE DISPLAYS, LTD | 2011-10-20 | — | — | US | claimed |
| WO-2010084160-A1 | PHENYLCYCLOPROPYLAMINE DERIVATIVES AND THEIR MEDICAL USE | ORYZON GENOMICS S.A. (ES) | 2010-07-29 | — | — | WO | claimed |
| EP-3430015-B1 | METHODS TO DETERMINE KDM1A TARGET ENGAGEMENT AND CHEMOPROBES USEFUL THEREFOR | ORYZON GENOMICS SA (ES) | 2025-08-06 | — | — | EP | disclosed |
| US-20250017933-A1 | CANCER TREATMENT USING LSD1 INHIBITORS AND PLK1 INHIBITORS | CARDIFF ONCOLOGY, INC. | 2025-01-16 | — | — | US | disclosed |
| US-12195783-B2 | Methods to determine KDM1A target engagement and chemoprobes useful therefor | ORYZON GENOMICS S.A. (ES) | 2025-01-14 | — | — | US | disclosed |
| EP-3013424-B1 | LSD INHIBITORS FOR MODULATING CANCER STEM CELLS | EPIAXIS THERAPEUTICS PTY LTD (AU) | 2024-09-25 | — | — | EP | disclosed |
| US-20120004262-A1 | PHENYLCYCLOPROPYLAMINE DERIVATIVES AND THEIR MEDICAL USE | ORYZON GENOMICS, S.A. (ES) | 2012-01-05 | — | — | US | disclosed |
| EP-2389362-A1 | PHENYLCYCLOPROPYLAMINE DERIVATIVES AND THEIR MEDICAL USE | Oryzon Genomics, S.A. (ES) | 2011-11-30 | — | — | EP | disclosed |
| US-20110252680-A1 | Surface mounted frame arrangement | ROSE DISPLAYS, LTD | 2011-10-20 | — | — | US | disclosed |
| WO-2010084160-A1 | PHENYLCYCLOPROPYLAMINE DERIVATIVES AND THEIR MEDICAL USE | ORYZON GENOMICS S.A. (ES) | 2010-07-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250017933-A1 | CANCER TREATMENT USING LSD1 INHIBITORS AND PLK1 INHIBITORS | PLK1, KDM1B, EZH2 | KDM1A 5/4885MAOB 952/4885MAOA 1205/4885 |
| US-20200054578-A1 | LSD1 INHIBITORS AS SKELETAL MUSCLE HYPERTROPHY INDUCERS | KDM1B, KDM1A, CPT1B | KDM1A 2/4885MAOB 534/4885MAOA 763/4885 |
| US-12195783-B2 | Methods to determine KDM1A target engagement and chemoprobes useful therefor | KDM1B, KDM1A, KDM7A | KDM1A 2/4885MAOB 3928/4885MAOA 4155/4885 |
| US-20120004262-A1 | PHENYLCYCLOPROPYLAMINE DERIVATIVES AND THEIR MEDICAL USE | PNMT, ABCB1, SNCA | KDM1A 1515/4885MAOB 143/4885MAOA 80/4885 |
| US-20160045456-A1 | PHENYLCYCLOPROPYLAMINE DERIVATIVES AND THEIR MEDICAL USE | PNMT, ABCB1, SNCA | KDM1A 1515/4885MAOB 143/4885MAOA 80/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.