Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 10/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2398269 | 0.87 | GLA (0.67) | GLAUSP2GAACNR2CA12 | |
| SCHEMBL29199488 | 0.82 | GLA (0.45) | GLACNR2MMP2MMP3MMP13 | |
| SCHEMBL29172462 | 0.82 | GLA (0.45) | GLACNR2MMP2MMP3MMP13 | |
| SCHEMBL14798321 | 0.78 | GLA (0.55) | GLAUSP2GAACNR2TAS2R14 | |
| SCHEMBL29199474 | 0.75 | GLA (0.48) | GLACNR2MMP2MMP3MMP13 | |
| SCHEMBL29172469 | 0.74 | GLA (0.48) | GLAUSP2GAACNR2MMP2 | |
| SCHEMBL31296435 | 0.73 | USP2 (0.56) | GLAUSP2GAAMMP2MMP13 | |
| SCHEMBL28858053 | 0.73 | C5AR1 (0.44) | GLAGAACNR2MMP2MMP3 | |
| SCHEMBL21113603 | 0.71 | CA12 (0.54) | GLACNR2CA12CA9HTT | |
| SCHEMBL15147424 | 0.71 | GLA (0.61) | GLAUSP2GAACNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8013171-B2 | Axially asymmetric ester compound and production method thereof | NATIONAL UNIVERSITY CORPORATION TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY (JP) | 2011-09-06 | — | — | US | disclosed |
| US-8013171-B2 | Axially asymmetric ester compound and production method thereof | NATIONAL UNIVERSITY CORPORATION TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY (JP) | 2011-09-06 | — | — | US | disclosed |
| US-20090299076-A1 | Axially asymmetric ester compound and production method thereof | NATIONAL UNIVERSITY CORPORATION TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY (JP) | 2009-12-03 | — | — | US | disclosed |
| US-20090299076-A1 | Axially asymmetric ester compound and production method thereof | NATIONAL UNIVERSITY CORPORATION TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY (JP) | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090299076-A1 | Axially asymmetric ester compound and production method thereof | SQLE, COASY, TBC1D5 | GLA 1415/4885USP2 4779/4885GAA 1685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.