Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29199472 | 0.94 | PSEN1 (0.48) | GLAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL28446732 | 0.94 | TAS2R14 (0.45) | GLAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL29199488 | 0.94 | GLA (0.45) | GLAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL28439886 | 0.92 | LMNA (0.45) | GLAKEAP1ALDH1A1MMP13 | |
| SCHEMBL28584130 | 0.92 | RORC (0.46) | GLAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL1177271 | 0.83 | GLA (0.53) | GLAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL21595413 | 0.82 | GLA (0.51) | GLAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL23297778 | 0.76 | SMN1; SMN2 (0.51) | GLAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL12330056 | 0.76 | GLA (0.46) | GLAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL10017634 | 0.75 | CNR2 (0.54) | GLAPSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117945974-A | High-efficiency palladium-catalyzed difunctional carbonyl derivative and preparation method thereof | 兰州城市学院 | 2024-04-30 | — | — | CN | claimed |
| CN-117945974-A | High-efficiency palladium-catalyzed difunctional carbonyl derivative and preparation method thereof | 兰州城市学院 | 2024-04-30 | — | — | CN | disclosed |