Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.71 |
| ▸ | ACHE | P22303 | 2/20 | 0.71 |
| ▸ | MGAM | O43451 | 1/20 | 0.71 |
| ▸ | SI | P14410 | 1/20 | 0.71 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.71 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.71 |
| ▸ | MAOA | P21397 | 1/20 | 0.68 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.50 |
| ▸ | HPGD | P15428 | 9/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 5/20 | 0.45 |
| ▸ | CA12 | O43570 | 4/20 | 0.45 |
| ▸ | CA1 | P00915 | 4/20 | 0.45 |
| ▸ | CA7 | P43166 | 4/20 | 0.45 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15444405 | 0.87 | MAOA (0.67) | GAAACHEMGAMSIPTPN1 | |
| SCHEMBL4740846 | 0.86 | MAOA (0.79) | GAAACHEMGAMSIPTPN1 | |
| SCHEMBL14303565 | 0.86 | MAOA (0.66) | GAAACHEMGAMSIPTPN1 | |
| SCHEMBL14303567 | 0.86 | MAOA (0.79) | GAAACHEMGAMSIPTPN1 | |
| SCHEMBL4744411 | 0.86 | GAA (0.65) | GAAACHEMGAMSIPTPN1 | |
| SCHEMBL14105711 | 0.85 | GAA (0.64) | GAAACHEMGAMSIPTPN1 | |
| Decursinol SCHEMBL3895912 | 0.83 | GAA (1.00) | GAAACHEMGAMSIPTPN1 | |
| Decursinol SCHEMBL14105325 | 0.83 | GAA (1.00) | GAAACHEMGAMSIPTPN1 | |
| SCHEMBL14105337 | 0.83 | GAA (0.76) | GAAACHEMGAMSIPTPN1 | |
| Decursinol SCHEMBL18845442 | 0.83 | GAA (1.00) | GAAACHEMGAMSIPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021221208-A1 | DIHYDROPYRANO[3,2-G]CROMEN-2-ONE DERIVATIVE AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER, COMPRISING SAME AS ACTIVE INGREDIENT | 재단법인 대구경북첨단의료산업진흥재단 (KR) | 2021-11-04 | — | — | WO | disclosed |