Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 8/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15614975 | 0.71 | NUDT1 (0.53) | KDM4EATMTAAR1TSHRMAPK1 | |
| SCHEMBL16905396 | 0.70 | NUDT1 (0.47) | KDM4EATMTAAR1TSHRMAPK1 | |
| SCHEMBL27824291 | 0.70 | KDM4E (0.67) | KDM4EATMTAAR1TSHRMAPK1 | |
| SCHEMBL29351641 | 0.68 | ATM (1.00) | KDM4EATMTAAR1TSHRMAPK1 | |
| SCHEMBL210639 | 0.68 | ATM (1.00) | KDM4EATMTAAR1TSHRMAPK1 | |
| Bromide SCHEMBL11470661 | 0.67 | ATM (0.96) | KDM4EATMTAAR1TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL3745006 | 0.67 | ATM (0.96) | KDM4EATMTAAR1TSHRMAPK1 | |
| Iodide SCHEMBL10518637 | 0.67 | ATM (0.96) | KDM4EATMTAAR1TSHRMAPK1 | |
| SCHEMBL18970227 | 0.67 | KDM4E (0.41) | KDM4EATMTAAR1TSHRMAPK1 | |
| SCHEMBL17186198 | 0.67 | NUDT1 (0.51) | KDM4EATMTAAR1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021220053-A2 | COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES WITH MODULAR FUNCTIONALITY | Sixfold Bioscience Ltd. (GB) | 2021-11-04 | — | — | WO | disclosed |