Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24702273 | 0.80 | ALDH1A1 (0.32) | MEN1POLBKMT2AGAA | |
| SCHEMBL23976467 | 0.79 | POLB (0.36) | MEN1POLBKMT2AHDAC1HDAC8 | |
| SCHEMBL25932387 | 0.79 | POLB (0.38) | MEN1POLBKMT2AHDAC1HDAC8 | |
| SCHEMBL23975804 | 0.78 | POLB (0.37) | MEN1POLBKMT2AHDAC1HDAC8 | |
| SCHEMBL30225307 | 0.78 | POLB (0.37) | MEN1POLBKMT2AHDAC1HDAC8 | |
| SCHEMBL30225306 | 0.78 | POLB (0.37) | MEN1POLBKMT2AHDAC1HDAC8 | |
| SCHEMBL27209476 | 0.78 | POLB (0.37) | MEN1POLBKMT2AHDAC1HDAC8 | |
| SCHEMBL23986913 | 0.77 | MEN1 (0.34) | MEN1POLBKMT2AHDAC1HDAC8 | |
| SCHEMBL30225189 | 0.75 | POLB (0.40) | MEN1POLBKMT2AHDAC1HDAC8 | |
| SCHEMBL23975730 | 0.75 | POLB (0.40) | MEN1POLBKMT2AHDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222363-A1 | CYCLOALKYL PYRIMIDINES AS FERROPORTIN INHIBITORS | GLOBAL BLOOD THERAPEUTICS, INC. (US) | 2021-11-04 | — | — | WO | disclosed |