SCHEMBL23987261

SCHEMBL23987261

CC(C)CC1(C(=O)OCc2ccccc2)CC1(C)C

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
GRM5 P41594 1/20 0.43
DDB1 Q16531 1/20 0.43
CRBN Q96SW2 1/20 0.43
MAPK1 P28482 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
SLC6A2 P23975 1/20 0.41
SLC6A3 Q01959 1/20 0.41
KMT2A Q03164 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CYP3A4 P08684 1/20 0.41
CTSK P43235 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13863548 0.84 ALDH1A1 (0.50) ALDH1A1GRM5DDB1CRBNMAPK1
SCHEMBL12961112 0.80 ALDH1A1 (0.46) ALDH1A1GRM5DDB1CRBNMAPK1
SCHEMBL12027689 0.79 ALDH1A1 (0.55) ALDH1A1GRM5DDB1CRBNMAPK1
SCHEMBL8260201 0.77 ALDH1A1 (0.46) ALDH1A1DDB1CRBNMAPK1L3MBTL1
SCHEMBL16347929 0.76 ALDH1A1 (0.45) ALDH1A1DDB1CRBN
SCHEMBL15114660 0.75 ALDH1A1 (0.50) ALDH1A1DDB1CRBNMAPK1L3MBTL1
SCHEMBL16700331 0.75 ALDH1A1 (0.50) ALDH1A1DDB1CRBNMAPK1L3MBTL1
SCHEMBL21446090 0.73 DDB1 (0.42) ALDH1A1DDB1CRBNCTSK
SCHEMBL13518540 0.73 ALDH1A1 (0.51) ALDH1A1DDB1CRBNMAPK1L3MBTL1
SCHEMBL25326042 0.72 ALDH1A1 (0.47) ALDH1A1DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021219509-A1 DNQ-FREE CHEMICALLY AMPLIFIED RESIST COMPOSITION MERCK PATENT GMBH (DE) 2021-11-04 WO disclosed