Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 15/20 | 0.59 |
| ▸ | FLT1 | P17948 | 4/20 | 0.47 |
| ▸ | FLT4 | P35916 | 4/20 | 0.47 |
| ▸ | BMP4 | P12644 | 1/20 | 0.45 |
| ▸ | BMPR1A | P36894 | 2/20 | 0.43 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.43 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.43 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.43 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.43 |
| ▸ | BMPR2 | Q13873 | 1/20 | 0.43 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.43 |
| ▸ | GAK | O14976 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24409677 | 0.84 | ACVR1 (0.64) | KDRBMP4BMPR1AACVR1BMPR1B | |
| SCHEMBL23988764 | 0.76 | ACVR1 (0.69) | KDRFLT1FLT4BMPR1AACVR1 | |
| SCHEMBL7618559 | 0.76 | KDR (0.77) | KDRFLT1FLT4BMP4BMPR1A | |
| SCHEMBL7618989 | 0.75 | KDR (1.00) | KDRFLT1FLT4BMP4BMPR1A | |
| SCHEMBL23988761 | 0.75 | KDR (0.67) | KDRFLT1FLT4BMP4BMPR1A | |
| SCHEMBL23988803 | 0.74 | KDR (0.59) | KDRFLT1FLT4BMP4BMPR1A | |
| SCHEMBL23988765 | 0.73 | KDR (0.68) | KDRFLT1FLT4BMP4BMPR1A | |
| SCHEMBL23988902 | 0.73 | KDR (0.54) | KDRFLT1FLT4BMPR1AACVR1 | |
| SCHEMBL23988994 | 0.72 | KDR (0.67) | KDRFLT1FLT4BMP4BMPR1A | |
| SCHEMBL12779953 | 0.72 | KDR (0.62) | KDRFLT1FLT4BMP4BMPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222875-A1 | METHODS OF USING ALK2 INHIBITORS | KEROS THERAPEUTICS, INC. (US) | 2021-11-04 | — | — | WO | disclosed |