Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVR1 | Q04771 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23988699 | 0.88 | ACVR1 (0.69) | ACVR1 | |
| SCHEMBL23988880 | 0.82 | ACVR1 (0.58) | ACVR1 | |
| SCHEMBL23988847 | 0.82 | ACVR1 (0.60) | ACVR1 | |
| SCHEMBL23988861 | 0.82 | BMP4 (0.64) | ACVR1 | |
| SCHEMBL23988873 | 0.80 | ACVR1 (0.62) | ACVR1 | |
| SCHEMBL23988890 | 0.78 | ACVR1 (0.61) | ACVR1 | |
| SCHEMBL23988731 | 0.78 | ACVR1 (0.55) | ACVR1 | |
| SCHEMBL23988856 | 0.77 | BMP4 (0.55) | ACVR1 | |
| SCHEMBL23988791 | 0.77 | BMP4 (0.67) | ACVR1 | |
| SCHEMBL23988744 | 0.76 | ACVR1 (0.60) | ACVR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222875-A1 | METHODS OF USING ALK2 INHIBITORS | KEROS THERAPEUTICS, INC. (US) | 2021-11-04 | — | — | WO | disclosed |