Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7220211 | 0.76 | ALDH1A1 (0.37) | ALDH1A1TSHRNFE2L2MAOBCYP2A6 | |
| SCHEMBL17331000 | 0.73 | ALDH1A1 (0.38) | ALDH1A1TSHRNFE2L2MAOBCYP2A6 | |
| SCHEMBL67469 | 0.72 | ALDH1A1 (0.41) | ALDH1A1TSHRNFE2L2MAOBCYP2A6 | |
| SCHEMBL9341987 | 0.70 | HTR2A (0.36) | HTR2AALDH1A1TSHRNFE2L2MAOB | |
| SCHEMBL5670111 | 0.69 | ALDH1A1 (0.38) | ALDH1A1TSHRNFE2L2MAOBCYP2A6 | |
| SCHEMBL512987 | 0.67 | ALDH1A1 (0.41) | ALDH1A1TSHRNFE2L2MAOBCYP2A6 | |
| SCHEMBL17330613 | 0.67 | ALDH1A1 (0.36) | ALDH1A1TSHRNFE2L2MAOBCYP2A6 | |
| SCHEMBL23683764 | 0.65 | HTR2A (0.41) | HTR2ANFE2L2MAOBAHRCYP1A2 | |
| SCHEMBL5669653 | 0.65 | ALDH1A1 (0.35) | ALDH1A1TSHRNFE2L2MAOBCYP2A6 | |
| SCHEMBL19713580 | 0.64 | EGFR (0.33) | ALDH1A1TSHRNFE2L2MAOBCYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8252559-B2 | Methods and systems for selective fluorination of organic molecules | THE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-08-28 | — | — | US | disclosed |
| US-8026085-B2 | Methods and systems for selective fluorination of organic molecules | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2011-09-27 | — | — | US | disclosed |
| US-20090209010-A1 | METHODS AND SYSTEMS FOR SELECTIVE FLUORINATION OF ORGANIC MOLECULES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2009-08-20 | — | — | US | disclosed |
| EP-2069513-A2 | METHODS AND SYSTEMS FOR SELECTIVE FLUORINATION OF ORGANIC MOLECULES | California Institute of Technology (US) | 2009-06-17 | — | — | EP | disclosed |
| US-20090061471-A1 | Methods and systems for selective fluorination of organic molecules | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2009-03-05 | — | — | US | disclosed |
| WO-2008016709-A9 | METHODS AND SYSTEMS FOR SELECTIVE FLUORINATION OF ORGANIC MOLECULES | CALIFORNIA INST OF TECHN (US) | 2008-05-29 | — | — | WO | disclosed |
| WO-2008016709-A2 | METHODS AND SYSTEMS FOR SELECTIVE FLUORINATION OF ORGANIC MOLECULES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2008-02-07 | — | — | WO | disclosed |