Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 5/20 | 0.52 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.49 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.46 |
| ▸ | ATG7 | O95352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | STAT6 | P42226 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23989400 | 1.00 | ADK (0.52) | ADKPRMT5SLC29A1ATG7MAPK1 | |
| SCHEMBL23989402 | 0.91 | ADK (0.61) | ADKSLC29A1MAPK1TDP1ALDH1A1 | |
| SCHEMBL25352899 | 0.91 | ADK (0.61) | ADKSLC29A1MAPK1TDP1ALDH1A1 | |
| SCHEMBL23989110 | 0.91 | ADK (0.61) | ADKSLC29A1MAPK1TDP1ALDH1A1 | |
| SCHEMBL25352927 | 0.84 | ADK (0.62) | ADKPRMT5SLC29A1 | |
| SCHEMBL15948775 | 0.84 | PRMT5 (0.60) | ADKPRMT5SLC29A1MAPK1ALDH1A1 | |
| SCHEMBL30536337 | 0.84 | ADK (0.62) | ADKPRMT5SLC29A1 | |
| SCHEMBL23989132 | 0.84 | ADK (0.62) | ADKPRMT5SLC29A1 | |
| SCHEMBL25353444 | 0.82 | TP53 (0.57) | ADKPRMT5SLC29A1STAT6HIF1A | |
| SCHEMBL8970336 | 0.81 | SLC29A1 (0.58) | SLC29A1MAPK1STAT6TP53DOT1L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210340169-A1 | CYCLIC DINUCLEOTIDE COMPOUND AND USES THEREOF | SHANGHAI JEYOU PHARMACEUTICAL CO., LTD. (CN) | 2021-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210340169-A1 | CYCLIC DINUCLEOTIDE COMPOUND AND USES THEREOF | STING1, CGAS, TLR9 | ADK 394/4885PRMT5 2792/4885SLC29A1 442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.