Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.50 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.50 |
| ▸ | B4GALT1 | P15291 | 1/20 | 0.49 |
| ▸ | HRAS | P01112 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18875811 | 0.87 | MAPK1 (0.67) | MAPK1LGALS8MEN1KMT2ALGALS3 | |
| SCHEMBL17283441 | 0.86 | MAPK1 (0.60) | MAPK1LGALS8MEN1KMT2ALGALS3 | |
| SCHEMBL19509829 | 0.86 | LGALS8 (0.52) | LGALS8POLB | |
| SCHEMBL19509830 | 0.86 | LGALS8 (0.52) | LGALS8POLB | |
| SCHEMBL19500446 | 0.86 | LGALS8 (0.52) | LGALS8POLB | |
| SCHEMBL22855653 | 0.86 | MAPK1 (0.57) | MAPK1LGALS8MEN1KMT2ALGALS3 | |
| SCHEMBL24699869 | 0.86 | MAPK1 (0.57) | MAPK1LGALS8MEN1KMT2ALGALS3 | |
| SCHEMBL20643560 | 0.85 | MAPK1 (0.58) | MAPK1MEN1KMT2AHRASPOLB | |
| SCHEMBL13031052 | 0.85 | MAPK1 (0.58) | MAPK1MEN1KMT2AHRASPOLB | |
| SCHEMBL21097246 | 0.85 | MAPK1 (0.58) | MAPK1MEN1KMT2AHRASPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210330677-A1 | PKC INHIBITORS FOR THE TREATMENT OF SEPTIC CHOLESTASIS WITH CTM TARGETING | SMARTDYELIVERY GMBH (DE) | 2021-10-28 | — | — | US | disclosed |