Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15222421 | 0.92 | ALDH1A1 (0.40) | ALDH1A1HRH3 | |
| SCHEMBL10254957 | 0.92 | HRH3 (0.32) | ALDH1A1HRH3 | |
| SCHEMBL16663585 | 0.92 | HRH3 (0.32) | ALDH1A1HRH3 | |
| SCHEMBL21210713 | 0.92 | HRH3 (0.32) | ALDH1A1HRH3 | |
| SCHEMBL25005424 | 0.89 | HRH3 (0.33) | HRH3 | |
| SCHEMBL24669047 | 0.86 | ALDH1A1 (0.37) | ALDH1A1HRH3 | |
| SCHEMBL23514642 | 0.86 | ALDH1A1 (0.37) | ALDH1A1HRH3 | |
| SCHEMBL2741645 | 0.86 | ALDH1A1 (0.37) | ALDH1A1HRH3 | |
| SCHEMBL24669048 | 0.86 | ALDH1A1 (0.37) | ALDH1A1HRH3 | |
| SCHEMBL12040654 | 0.86 | HRH3 (0.32) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230039553-A1 | CD73 COMPOUNDS | GILEAD SCIENCES, INC. | 2023-02-09 | — | — | US | disclosed |
| WO-2021222522-A1 | CD73 INHIBITING 2,4-DIOXOPYRIMIDINE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2021-11-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230039553-A1 | CD73 COMPOUNDS | ENTPD5, ENTPD1, NT5E | ALDH1A1 347/4885HRH3 2928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.