Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL81000 | 0.98 | DNM1 (0.58) | DNM1MEN1KMT2ATP53SMN1; SMN2 | |
| Hydrogen Sulfide SCHEMBL5998244 | 0.98 | DNM1 (0.58) | DNM1MEN1KMT2ATP53SMN1; SMN2 | |
| Tetrabuthylammonium SCHEMBL17275219 | 0.96 | DNM1 (0.61) | DNM1MEN1KMT2ATP53SMN1; SMN2 | |
| Bromide SCHEMBL29110289 | 0.96 | DNM1 (0.59) | DNM1MEN1KMT2ATP53SMN1; SMN2 | |
| Bromide SCHEMBL28701241 | 0.96 | DNM1 (0.56) | DNM1MEN1KMT2ATP53SMN1; SMN2 | |
| Bromide SCHEMBL240143 | 0.96 | DNM1 (0.59) | DNM1MEN1KMT2ATP53SMN1; SMN2 | |
| Hydrogen Sulfide SCHEMBL5998240 | 0.96 | DNM1 (0.56) | DNM1MEN1KMT2ATP53SMN1; SMN2 | |
| Iodide SCHEMBL5091862 | 0.96 | DNM1 (0.56) | DNM1MEN1KMT2ATP53SMN1; SMN2 | |
| Fluoride Ion SCHEMBL636828 | 0.96 | DNM1 (0.56) | DNM1MEN1KMT2ATP53SMN1; SMN2 | |
| Bromide SCHEMBL29110287 | 0.96 | DNM1 (0.56) | DNM1MEN1KMT2ATP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 472 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114105980-B | Preparation method of Lu Meipai-one intermediate compound and lumepiquat chloride intermediate compound | 南方科技大学坪山生物医药研究院 | 2024-04-16 | — | — | CN | claimed |
| CN-114105985-B | Method for constructing Lu Meipai long intermediate by asymmetric hydrogenation and lumepiquat chloride intermediate | 南方科技大学坪山生物医药研究院 | 2024-04-16 | — | — | CN | claimed |
| CN-113087625-B | Method for synthesizing benzyl acetate by utilizing combined catalytic system | 潜江新亿宏有机化工有限公司 | 2022-04-01 | — | — | CN | claimed |
| CN-114105980-A | Preparation method of rumepilone intermediate compound and rumepilone intermediate compound | 南方科技大学坪山生物医药研究院 | 2022-03-01 | — | — | CN | claimed |
| CN-114105985-A | Method for constructing rumepilone intermediate through asymmetric hydrogenation and rumepilone intermediate | 南方科技大学坪山生物医药研究院 | 2022-03-01 | — | — | CN | claimed |
| CN-108148394-B | Storage-stable one-component polyurethane prepregs from polyurethane compositions and moldings produced therefrom | 赢创运营有限公司 | 2021-12-28 | — | — | CN | claimed |
| CN-113087625-A | Method for synthesizing benzyl acetate by utilizing combined catalytic system | 潜江新亿宏有机化工有限公司 | 2021-07-09 | — | — | CN | claimed |
| EP-3330311-B1 | STORAGE STABLE 1K-POLYURETHANE-PREPREGS AND MOULDED ARTICLE MADE FROM SAME ON THE BASIS OF A POLYURETHANE COMPOSITION | EVONIK OPERATIONS GMBH (DE) | 2021-05-05 | — | — | EP | claimed |
| US-10633519-B2 | Storage-stable polyurethane prepregs and mouldings produced therefrom composed of a polyurethane composition with liquid resin components | EVONIK OPERATIONS GMBH (DE) | 2020-04-28 | — | — | US | claimed |
| US-10626236-B2 | Storage-stable one-component polyurethane prepregs and shaped bodies composed of polyurethane composition that have been produced therefrom | EVONIK OPERATIONS GMBH (DE) | 2020-04-21 | — | — | US | claimed |
| US-20060224016-A1 | Process for preparing 3-aminophenylacetylenes | FUJI PHOTO FILM CO., LTD. | 2006-10-05 | — | — | US | claimed |
| EP-0743574-B1 | Migration imaging members | XEROX CORP (US) | 2000-12-27 | — | — | EP | claimed |
| EP-0743573-B1 | Method for obtaining image contrast migration imaging members | XEROX CORP (US) | 2000-09-06 | — | — | EP | claimed |
| EP-0615857-B1 | Recording sheets containing monoammonium compounds | XEROX CORP (US) | 1998-11-11 | — | — | EP | claimed |
| EP-0743573-A2 | Method for obtaining image contrast migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| EP-0743574-A2 | Migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| US-5563014-A | SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT | XEROX CORPORATION (US) | 1996-10-08 | — | — | US | claimed |
| US-5514505-A | SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE | XEROX CORPORATION (US) | 1996-05-07 | — | — | US | claimed |
| EP-0615857-A1 | Recording sheets containing monoammonium compounds | XEROX CORPORATION (US) | 1994-09-21 | — | — | EP | claimed |
| US-5320902-A | Suitable for use in ink jet printing | XEROX CORPORATION (US) | 1994-06-14 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060224016-A1 | Process for preparing 3-aminophenylacetylenes | NAT1, NAT10, KAT7 | ACHE 1828/4885DNM1 4727/4885MEN1 1559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.