⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25005876 | 1.00 | — | — | |
| SCHEMBL30181794 | 1.00 | — | — | |
| SCHEMBL30224195 | 1.00 | — | — | |
| SCHEMBL30224760 | 0.80 | HTR2A (0.31) | — | |
| SCHEMBL23994136 | 0.80 | NT5E (0.33) | — | |
| SCHEMBL30181463 | 0.80 | NT5E (0.33) | — | |
| SCHEMBL23994557 | 0.80 | HTR2A (0.32) | — | |
| SCHEMBL30181922 | 0.80 | NT5E (0.33) | — | |
| SCHEMBL23994571 | 0.79 | KCNJ6 (0.39) | — | |
| SCHEMBL30224579 | 0.78 | HTR2A (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250270174-A1 | CD73 COMPOUNDS | GILEAD SCIENCES, INC. | 2025-08-28 | — | — | US | disclosed |
| US-20240279186-A1 | CD73 COMPOUNDS | GILEAD SCIENCES, INC. | 2024-08-22 | — | — | US | disclosed |
| US-11919869-B2 | CD73 compounds | GILEAD SCIENCES, INC. (US) | 2024-03-05 | — | — | US | disclosed |
| US-20230183189-A1 | CD73 COMPOUNDS | GILEAD SCIENCES, INC. | 2023-06-15 | — | — | US | disclosed |
| US-20230183189-A1 | CD73 COMPOUNDS | GILEAD SCIENCES, INC. | 2023-06-15 | — | — | US | disclosed |
| US-20230183189-A1 | CD73 COMPOUNDS | GILEAD SCIENCES, INC. | 2023-06-15 | — | — | US | disclosed |
| US-20230039553-A1 | CD73 COMPOUNDS | GILEAD SCIENCES, INC. | 2023-02-09 | — | — | US | disclosed |
| WO-2021222522-A1 | CD73 INHIBITING 2,4-DIOXOPYRIMIDINE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2021-11-04 | — | — | WO | disclosed |