Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 7/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25004875 | 0.83 | PDE10A (0.32) | PDE10A | |
| SCHEMBL23995229 | 0.81 | PDE10A (0.32) | PDE10A | |
| SCHEMBL25004868 | 0.79 | PDE10A (0.33) | PDE10A | |
| SCHEMBL23994612 | 0.78 | PDE10A (0.34) | PDE10A | |
| SCHEMBL23995228 | 0.77 | PDE10A (0.44) | PDE10A | |
| SCHEMBL23993465 | 0.69 | — | — | |
| SCHEMBL30181632 | 0.69 | — | — | |
| SCHEMBL30181631 | 0.69 | — | — | |
| SCHEMBL25005312 | 0.69 | — | — | |
| SCHEMBL23993485 | 0.68 | MTNR1A (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222522-A1 | CD73 INHIBITING 2,4-DIOXOPYRIMIDINE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2021-11-04 | — | — | WO | disclosed |