Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 17/20 | 0.38 |
| ▸ | ACP1 | P24666 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25005175 | 0.81 | SYK (0.43) | SYKACP1MTOR | |
| SCHEMBL25004812 | 0.80 | SYK (0.45) | SYKACP1MTOR | |
| SCHEMBL23991557 | 0.77 | MTOR (0.38) | SYKACP1PPARDMTOR | |
| SCHEMBL30224465 | 0.77 | MTOR (0.38) | SYKACP1PPARDMTOR | |
| SCHEMBL23992849 | 0.76 | SYK (0.46) | SYKACP1 | |
| SCHEMBL25005507 | 0.75 | MDM2 (0.38) | SYKPPARDMTOR | |
| SCHEMBL30224642 | 0.75 | SYK (0.36) | SYKACP1PPARDMTOR | |
| SCHEMBL23994516 | 0.75 | SYK (0.36) | SYKACP1PPARDMTOR | |
| SCHEMBL23994425 | 0.74 | SYK (0.38) | SYKACP1PPARDMTOR | |
| SCHEMBL30224213 | 0.74 | SYK (0.38) | SYKACP1PPARDMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222522-A1 | CD73 INHIBITING 2,4-DIOXOPYRIMIDINE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2021-11-04 | — | — | WO | disclosed |