SCHEMBL23996253

SCHEMBL23996253

O=C1CN(Cc2ccc(C3(NS(=O)(=O)c4cccc(OC5CCCC5)c4)CCC3)cc2)C(O)N1

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ DUT P33316 11/20 0.44
▸ KAT6A Q92794 2/20 0.36
▸ SPHK2 Q9NRA0 2/20 0.32
▸ SPHK1 Q9NYA1 2/20 0.32
▸ EPHX2 P34913 1/20 0.32
▸ BACE1 P56817 1/20 0.31
▸ DDB1 Q16531 1/20 0.31
▸ CRBN Q96SW2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21536091 0.86 DUT (0.47) DUTKAT6ADDB1CRBN
SCHEMBL21536086 0.84 DUT (0.47) DUTKAT6ADDB1CRBN
SCHEMBL21536694 0.83 DUT (0.46) DUTKAT6ADDB1CRBN
SCHEMBL21536743 0.83 DUT (0.47) DUTKAT6ADDB1CRBN
SCHEMBL20374165 0.81 DUT (0.67) DUTKAT6AEPHX2
SCHEMBL21536094 0.80 DUT (0.45) DUTKAT6A
SCHEMBL21536580 0.80 DUT (0.45) DUTKAT6ADDB1CRBN
SCHEMBL21536622 0.79 DUT (0.47) DUTKAT6ADDB1CRBN
SCHEMBL21536095 0.79 DUT (0.46) DUTKAT6A
SCHEMBL21536745 0.78 DUT (0.46) DUTKAT6ADDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11168059-B2 Amino sulfonyl compounds CV6 THERAPEUTICS (NI) LIMITED (GB) 2021-11-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11168059-B2 Amino sulfonyl compounds DPYD, DNPEP, DUT DUT 3/4885KAT6A 3309/4885SPHK2 4170/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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