Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR5 | O14804 | 1/20 | 0.68 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.68 |
| ▸ | PCNA | P12004 | 3/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LIG1 | P18858 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29374539 | 0.81 | TAAR1 (1.00) | TAAR5TAAR1MEN1BLMKMT2A | |
| SCHEMBL359453 | 0.81 | TAAR1 (1.00) | TAAR5TAAR1MEN1BLMKMT2A | |
| SCHEMBL13886734 | 0.81 | TAAR5 (0.68) | TAAR5TAAR1PCNABLM | |
| SCHEMBL13886676 | 0.79 | TAAR5 (0.79) | TAAR5TAAR1PCNANR1I2PPARG | |
| SCHEMBL13894715 | 0.78 | TAAR5 (0.65) | TAAR5TAAR1PCNANR1I2PPARG | |
| SCHEMBL14230065 | 0.78 | TAAR5 (0.68) | TAAR5TAAR1PCNANR1I2PPARG | |
| SCHEMBL13886698 | 0.77 | TAAR5 (0.56) | TAAR5TAAR1PCNANR1I2PPARG | |
| SCHEMBL25773004 | 0.75 | TAAR1 (0.64) | TAAR5TAAR1PCNANR1I2PPARG | |
| SCHEMBL17141553 | 0.74 | TAAR5 (0.63) | TAAR5TAAR1PCNANR1I2PPARG | |
| SCHEMBL5742411 | 0.74 | TAAR5 (0.59) | TAAR5TAAR1PCNANR1I2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11666539-B2 | Synthetic lipid-like materials for brain delivery | TRUSTEES OF TUFTS COLLEGE (US) | 2023-06-06 | — | — | US | disclosed |
| US-11666539-B2 | Synthetic lipid-like materials for brain delivery | TRUSTEES OF TUFTS COLLEGE (US) | 2023-06-06 | — | — | US | disclosed |
| US-20210346307-A1 | SYNTHETIC LIPID-LIKE MATERIALS FOR BRAIN DELIVERY | TRUSTEES OF TUFTS COLLEGE | 2021-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11666539-B2 | Synthetic lipid-like materials for brain delivery | NPC1L1, FABP7, LIPA | TAAR5 1612/4885TAAR1 2228/4885PCNA 4884/4885 |
| US-20210346307-A1 | SYNTHETIC LIPID-LIKE MATERIALS FOR BRAIN DELIVERY | NPC1L1, FABP7, LIPA | TAAR5 1576/4885TAAR1 2172/4885PCNA 4884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.