SCHEMBL2399722

SCHEMBL2399722

C[C@H](Oc1ccc(Cl)cc1)C(=O)O

nearest known ligand 0.69

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.65
CYP2C9 P11712 2/20 0.65
CYP2C19 P33261 2/20 0.65
GAA P10253 1/20 0.65
PKM P14618 1/20 0.65
EPHX2 P34913 2/20 0.61
TDP1 Q9NUW8 1/20 0.59
MAP4K4 O95819 2/20 0.58
TSHR P16473 1/20 0.57
HTR2A P28223 1/20 0.57
HTR2C P28335 1/20 0.57
HTR2B P41595 1/20 0.57
PPARG P37231 6/20 0.54
PPARA Q07869 6/20 0.54
POLB P06746 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL607372 1.00 CYP1A2 (0.65) CYP1A2CYP2C9CYP2C19GAAPKM
SCHEMBL117259 1.00 CYP1A2 (0.65) CYP1A2CYP2C9CYP2C19GAAPKM
Ammonia Solution, Strong SCHEMBL28260028 0.98 CYP1A2 (0.62) CYP1A2CYP2C9CYP2C19GAAPKM
SCHEMBL20591019 0.98 CYP1A2 (0.62) CYP1A2CYP2C9CYP2C19GAAPKM
SCHEMBL27765434 0.98 CYP1A2 (0.62) CYP1A2CYP2C9CYP2C19GAAPKM
Hydrochloric Acid SCHEMBL11632943 0.98 CYP1A2 (0.62) CYP1A2CYP2C9CYP2C19GAAPKM
SCHEMBL3217144 0.94 CYP1A2 (0.59) CYP1A2CYP2C9CYP2C19GAAPKM
SCHEMBL135587 0.94 CYP1A2 (0.59) CYP1A2CYP2C9CYP2C19GAAPKM
Dimethylamine SCHEMBL28509130 0.94 EPHX2 (0.60) CYP1A2CYP2C9CYP2C19GAAPKM
Isopropylamine SCHEMBL27635387 0.94 CYP1A2 (0.59) CYP1A2CYP2C9CYP2C19GAAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3723745-A1 PHENOXY ACIDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD Pharma A/S (DK) 2020-10-21 EP claimed
CN-111587109-A Phenoxy acids for the treatment of neuromuscular disorders NMD制药股份公司 2020-08-25 CN claimed
WO-2019115777-A1 PHENOXY ACIDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2019-06-20 WO claimed
US-20190183833-A1 Compounds For The Treatment Of Neuromuscular Disorders NMD PHARMA APS 2019-06-20 US claimed
US-20190183834-A1 Compounds For The Treatment Of Neuromuscular Disorders NMD PHARMA A/S (DK) 2019-06-20 US claimed
EP-1971222-A2 REDUCED SWEETNESS CONFECTIONARY COMPOSITIONS AND COATED/FILLED FOOD PRODUCTS GENERAL MILLS, INC. (US) 2008-09-24 EP claimed
WO-2007059066-A2 REDUCED SWEETNESS CONFECTIONARY COMPOSITIONS AND COATED/FILLED FOOD PRODUCTS GENERAL MILLS, INC. (US) 2007-05-24 WO claimed
US-20070110844-A1 REDUCED SWEETNESS CONFECTIONARY COMPOSITIONS AND COATED/FILLED FOOD PRODUCTS GENERAL MILLS, INC. 2007-05-17 US claimed
EP-1576194-B1 BACTERIAL STRAINS OF DELFTIA ACIDOVORANS MC1-R, THEIR PRODUCTION AND THEIR USE IN THE PRODUCTION OF THE R ENANTIOMERS OF 2-PHENOXYPROPIONIC ACID DERIVATIVES UFZ LEIPZIGHALLE GMBH (DE) 2006-05-31 EP claimed
EP-1576147-B1 BACTERIAL STRAINS DELFTIA ACIDOVORANS MC1-S, PRODUCTION AND USE THEREOF FOR THE PRODUCTION OF THE S ENANTIOMERS OF 2-PHENOXYPROPIONIC ACID DERIVATIVES UFZ LEIPZIGHALLE GMBH (DE) 2006-05-24 EP claimed
EP-0159864-B1 METHOD OF MODIFYING TASTE TATE & LYLE PUBLIC LIMITED COMPANY (GB) 1989-07-19 EP claimed
EP-3986873-B9 5-[(1S)-1-(4-BROMOPHENOXY)ETHYL]-2H-TETRAZOLE DERIVATIVES AND RELATED COMPOUNDS AS CLC-1 ION CHANNEL INHIBITORS FOR TREATING NEUROMUSCULAR DISORDERS NMD PHARMA AS (DK) 2024-05-29 EP disclosed
EP-3986873-B1 5-[(1S)-1-(4-BROMOPHENOXY)ETHYL]-2H-TETRAZOLE DERIVATIVES AND RELATED COMPOUNDS AS CLC-1 ION CHANNEL INHIBITORS FOR TREATING NEUROMUSCULAR DISORDERS NMD PHARMA AS (DK) 2023-11-15 EP disclosed
EP-3986873-B1 5-[(1S)-1-(4-BROMOPHENOXY)ETHYL]-2H-TETRAZOLE DERIVATIVES AND RELATED COMPOUNDS AS CLC-1 ION CHANNEL INHIBITORS FOR TREATING NEUROMUSCULAR DISORDERS NMD PHARMA AS (DK) 2023-11-15 EP disclosed
US-11730714-B2 Compounds for the treatment of neuromuscular disorders NMD PHARMA A/S (DK) 2023-08-22 US disclosed
EP-0159864-B1 METHOD OF MODIFYING TASTE TATE & LYLE PUBLIC LIMITED COMPANY (GB) 1989-07-19 EP disclosed
US-4803301-A Process for producing optically active 2-phenoxypropionic acid KIRIN BEER KABUSHIKI KAISHA (JP) 1989-02-07 US disclosed
US-4800162-A ENZYME-ACTIVATED MEMBRANE SEPRACOR, INC. (US) 1989-01-24 US disclosed
WO-1988007582-A1 METHOD FOR RESOLUTION OF STEREOISOMERS IN MULTIPHASE AND EXTRACTIVE MEMBRANE REACTORS SEPRACOR, INC. (US) 1988-10-06 WO disclosed
EP-0159864-A2 Method of modifying taste TATE & LYLE PUBLIC LIMITED COMPANY (GB) 1985-10-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11730714-B2 Compounds for the treatment of neuromuscular disorders RYR1, CACNB1, RYR2 CYP1A2 4681/4885CYP2C9 4788/4885CYP2C19 4866/4885
US-20190183834-A1 Compounds For The Treatment Of Neuromuscular Disorders RYR1, CACNB1, RYR2 CYP1A2 4681/4885CYP2C9 4788/4885CYP2C19 4866/4885
US-20190183833-A1 Compounds For The Treatment Of Neuromuscular Disorders RYR1, CACNB1, RYR2 CYP1A2 4681/4885CYP2C9 4788/4885CYP2C19 4866/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.