Sugi Predict

Sugi Predict / Compounds / SCHEMBL607372

SCHEMBL607372

SCHEMBL607372

C[C@@H](Oc1ccc(Cl)cc1)C(=O)O

nearest known ligand 0.69

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ CYP1A2 P05177 2/20 0.65
▸ CYP2C9 P11712 2/20 0.65
▸ CYP2C19 P33261 2/20 0.65
▸ GAA P10253 1/20 0.65
▸ PKM P14618 1/20 0.65
▸ EPHX2 P34913 2/20 0.61
▸ TDP1 Q9NUW8 1/20 0.59
▸ MAP4K4 O95819 2/20 0.58
▸ TSHR P16473 1/20 0.57
▸ HTR2A P28223 1/20 0.57
▸ HTR2C P28335 1/20 0.57
▸ HTR2B P41595 1/20 0.57
▸ PPARG P37231 6/20 0.54
▸ PPARA Q07869 6/20 0.54
▸ POLB P06746 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2399722 1.00 CYP1A2 (0.65) CYP1A2CYP2C9CYP2C19GAAPKM
SCHEMBL117259 1.00 CYP1A2 (0.65) CYP1A2CYP2C9CYP2C19GAAPKM
Ammonia Solution, Strong SCHEMBL28260028 0.98 CYP1A2 (0.62) CYP1A2CYP2C9CYP2C19GAAPKM
SCHEMBL20591019 0.98 CYP1A2 (0.62) CYP1A2CYP2C9CYP2C19GAAPKM
SCHEMBL27765434 0.98 CYP1A2 (0.62) CYP1A2CYP2C9CYP2C19GAAPKM
Hydrochloric Acid SCHEMBL11632943 0.98 CYP1A2 (0.62) CYP1A2CYP2C9CYP2C19GAAPKM
SCHEMBL3217144 0.94 CYP1A2 (0.59) CYP1A2CYP2C9CYP2C19GAAPKM
SCHEMBL135587 0.94 CYP1A2 (0.59) CYP1A2CYP2C9CYP2C19GAAPKM
Dimethylamine SCHEMBL28509130 0.94 EPHX2 (0.60) CYP1A2CYP2C9CYP2C19GAAPKM
Isopropylamine SCHEMBL27635387 0.94 CYP1A2 (0.59) CYP1A2CYP2C9CYP2C19GAAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116555360-A Method for biosynthesis of R- (+) -2- (4-hydroxyphenoxy) propionic acid 锦州四海生物化学有限公司 2023-08-08 — — CN claimed
CN-110563606-B Synthesis method of (R) -2- [4- (4-cyano-2-fluorophenoxy) phenoxy ] propionic acid 湖南速博生物技术有限公司 2022-06-21 — — CN claimed
CN-112679337-A Preparation method of (R) - (+) -2- (4-hydroxyphenoxy) propionic acid 锦州四海生物化学有限公司 2021-04-20 — — CN claimed
US-20190183833-A1 Compounds For The Treatment Of Neuromuscular Disorders NMD PHARMA APS 2019-06-20 — — US claimed
US-20120041225-A1 KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF VAIDYA NITEEN A (US) 2012-02-16 — — US claimed
EP-1981831-A2 KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF Vaidya, Niteen A. (US) 2008-10-22 — — EP claimed
WO-2007092264-A2 KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF VAIDYA NITEEN A (US) 2007-08-16 — — WO claimed
US-20070185346-A1 Kit for automated resolving agent selection and method thereof VAIDYA NITEEN A 2007-08-09 — — US claimed
US-11730714-B2 Compounds for the treatment of neuromuscular disorders NMD PHARMA A/S (DK) 2023-08-22 — — US disclosed
US-11730714-B2 Compounds for the treatment of neuromuscular disorders NMD PHARMA A/S (DK) 2023-08-22 — — US disclosed
CN-116555360-A Method for biosynthesis of R- (+) -2- (4-hydroxyphenoxy) propionic acid 锦州四海生物化学有限公司 2023-08-08 — — CN disclosed
CN-110563606-B Synthesis method of (R) -2- [4- (4-cyano-2-fluorophenoxy) phenoxy ] propionic acid 湖南速博生物技术有限公司 2022-06-21 — — CN disclosed
CN-110563606-B Synthesis method of (R) -2- [4- (4-cyano-2-fluorophenoxy) phenoxy ] propionic acid 湖南速博生物技术有限公司 2022-06-21 — — CN disclosed
US-11147788-B2 Compounds for the treatment of neuromuscular disorders NMD PHARMA A/S (DK) 2021-10-19 — — US disclosed
WO-1989009765-A1 ENZYMATIC RESOLUTION SYSTEMS AND COMPOUNDS USEFUL IN THE SYSTEMS AND THEIR REPARATIONS SEPRACOR, INC. (US) 1989-10-19 — — WO disclosed
US-4803301-A Process for producing optically active 2-phenoxypropionic acid KIRIN BEER KABUSHIKI KAISHA (JP) 1989-02-07 — — US disclosed
US-4800162-A ENZYME-ACTIVATED MEMBRANE SEPRACOR, INC. (US) 1989-01-24 — — US disclosed
WO-1988007582-A1 METHOD FOR RESOLUTION OF STEREOISOMERS IN MULTIPHASE AND EXTRACTIVE MEMBRANE REACTORS SEPRACOR, INC. (US) 1988-10-06 — — WO disclosed
US-4701210-A HERBICIDES SUNTORY LIMITED (JP) 1987-10-20 — — US disclosed
EP-0207690-A1 N-Substituted glutamic acid derivative and process for production and use thereof SUNTORY LIMITED (JP) 1987-01-07 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11730714-B2 Compounds for the treatment of neuromuscular disorders RYR1, CACNB1, RYR2 CYP1A2 4681/4885CYP2C9 4788/4885CYP2C19 4866/4885
US-11147788-B2 Compounds for the treatment of neuromuscular disorders RYR1, CACNB1, RYR2 CYP1A2 4681/4885CYP2C9 4788/4885CYP2C19 4866/4885
US-20120041225-A1 KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF ACKR3, KIT, C3AR1 CYP1A2 1252/4885CYP2C9 263/4885CYP2C19 1347/4885
US-20190183833-A1 Compounds For The Treatment Of Neuromuscular Disorders RYR1, CACNB1, RYR2 CYP1A2 4681/4885CYP2C9 4788/4885CYP2C19 4866/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.