SCHEMBL2399729

SCHEMBL2399729

CN(CCCCN1C(=O)c2ccccc2C1=O)CCCCN1C(=O)c2ccccc2C1=O

nearest known ligand 0.80

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAOB P27338 5/20 0.77
ACHE P22303 11/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2400817 0.98 MAOB (0.75) MAOBACHE
SCHEMBL13590254 0.95 ACHE (0.73) MAOBACHE
SCHEMBL14729859 0.95 MAOB (0.77) MAOBACHE
SCHEMBL25443484 0.93 MAOB (0.74) MAOBACHE
SCHEMBL25443471 0.93 MAOB (0.74) MAOBACHE
SCHEMBL13590077 0.91 ACHE (0.68) MAOBACHE
SCHEMBL4916280 0.89 MAOB (0.68) MAOBACHE
SCHEMBL29263614 0.88 ACHE (0.68) MAOBACHE
SCHEMBL4606466 0.88 MAOB (1.00) MAOBACHE
SCHEMBL16306674 0.87 MAOB (0.67) MAOBACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8017637-B2 Inhibitors of cdc phosphatases IPSEN PHARMA S.A.S. (FR) 2011-09-13 US disclosed
US-20090275624-A1 INHIBITORS OF CDC PHOSPHATASES SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) 2009-11-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090275624-A1 INHIBITORS OF CDC PHOSPHATASES CDC25C, CDC25A, CDC25B MAOB 3885/4885ACHE 4794/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.