Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | PLK4 | O00444 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | PAK4 | O96013 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | PRKCG | P05129 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11048476 | 0.73 | L3MBTL1 (0.56) | L3MBTL1ACACBHRH3KCNH2CDC7 | |
| SCHEMBL23997262 | 0.72 | MAPT (0.43) | KMT2ARAB9A | |
| SCHEMBL11200681 | 0.71 | L3MBTL1 (0.76) | L3MBTL1ACACBHRH3KCNH2CDC7 | |
| SCHEMBL23997165 | 0.71 | KMT2A (0.41) | KMT2ARAB9A | |
| SCHEMBL23997321 | 0.70 | — | — | |
| SCHEMBL27379105 | 0.70 | L3MBTL1 (0.86) | L3MBTL1ACACBHRH3KCNH2LMNA | |
| SCHEMBL180739 | 0.70 | L3MBTL1 (0.86) | L3MBTL1ACACBHRH3KCNH2LMNA | |
| SCHEMBL15491147 | 0.70 | L3MBTL1 (0.59) | L3MBTL1ACACBHRH3KCNH2CDC7 | |
| SCHEMBL23997213 | 0.69 | — | — | |
| SCHEMBL596252 | 0.69 | L3MBTL1 (0.96) | L3MBTL1ACACBHRH3KCNH2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021226003-A1 | IL4I1 INHIBITORS AND METHODS OF USE | MERCK SHARP & DOHME CORP. (US) | 2021-11-11 | — | — | WO | disclosed |