Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 14/20 | 0.39 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.34 |
| ▸ | GAK | O14976 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23999593 | 0.92 | SLC2A1 (0.37) | — | |
| SCHEMBL23999589 | 0.90 | KDR (0.40) | KDRRIPK2MAPKAPK2GAK | |
| SCHEMBL23999476 | 0.86 | KDR (0.39) | KDRRIPK2EGFRMAPKAPK2GAK | |
| SCHEMBL30180227 | 0.86 | KDR (0.39) | KDRRIPK2EGFRMAPKAPK2GAK | |
| SCHEMBL25495797 | 0.86 | KDR (0.37) | KDRRIPK2EGFRMAPKAPK2GAK | |
| SCHEMBL23999754 | 0.85 | MAPKAPK2 (0.45) | KDRRIPK2MAPKAPK2GAK | |
| SCHEMBL23999592 | 0.83 | KDR (0.39) | KDRRIPK2EGFRMAPKAPK2 | |
| SCHEMBL30180390 | 0.83 | MAPKAPK2 (0.40) | KDRMAPKAPK2 | |
| SCHEMBL23999481 | 0.83 | MAPKAPK2 (0.40) | KDRMAPKAPK2 | |
| SCHEMBL23999749 | 0.81 | SLC2A1 (0.47) | MAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021226519-A1 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2021-11-11 | — | — | WO | disclosed |